Gene Symbol | NUDT12 |
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Entrez Gene | 83594 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | nudix (nucleoside diphosphate linked moiety X)-type motif 12 |
Other Description | nucleoside diphosphate linked moiety X-type motif 12|nucleoside diphosphate-linked moiety X motif 12|nudix motif 12|peroxisomal NADH pyrophosphatase NUDT12 |
Swissprots | Q8TAL7 B3KUW2 Q9BQG2 |
Accessions | EAW49073 Q9BQG2 AK098066 BAG53574 AK304010 BAG64925 AK309942 AL136592 CAB66527 AM392531 CAL37409 BC026748 AAH26748 BC041099 AAH41099 BC042967 BU621954 CB131118 DB029218 DC417976 XM_005272095 XP_005272152 XM_005272097 XP_005272154 NM_001300741 NP_001287670 NM_031438 NP_113626 |
Function | Hydrolyzes NAD(P)H to NMNH and AMP (2',5'-ADP), and diadenosine diphosphate to AMP. Has also activity towards NAD(P)(+), ADP-ribose and diadenosine triphosphate. May act to regulate the concentration of peroxisomal nicotinamide nucleotide cofactors required for oxidative metabolism in this organelle. {ECO:0000269|PubMed:12790796}. |
Subcellular Location | Peroxisome {ECO:0000269|PubMed:12790796}. |
Top Pathways | Peroxisome, Nicotinate and nicotinamide metabolism |
NUDT12 CRISPR/Cas9 KO Plasmid (h) - sc-417081 from Santa Cruz Biotechnology
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NUDT12 HDR Plasmid (h) - sc-417081-HDR from Santa Cruz Biotechnology
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NUDT12 Double Nickase Plasmid (h) - sc-417081-NIC from Santa Cruz Biotechnology
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NUDT12 Double Nickase Plasmid (h2) - sc-417081-NIC-2 from Santa Cruz Biotechnology
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NUDT12 CRISPR Activation Plasmid (h) - sc-417081-ACT from Santa Cruz Biotechnology
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NUDT12 CRISPR Activation Plasmid (h2) - sc-417081-ACT-2 from Santa Cruz Biotechnology
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NUDT12 Lentiviral Activation Particles (h) - sc-417081-LAC from Santa Cruz Biotechnology
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NUDT12 Lentiviral Activation Particles (h2) - sc-417081-LAC-2 from Santa Cruz Biotechnology
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NUDT12 siRNA (h) - sc-91746 from Santa Cruz Biotechnology
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NUDT12 shRNA Plasmid (h) - sc-91746-SH from Santa Cruz Biotechnology
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NUDT12 shRNA (h) Lentiviral Particles - sc-91746-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU026281 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15590 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15590 from Sigma-Aldrich
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NUDT12 siRNA (Human) - CRJ3136 from Cohesion Biosciences
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NUDT12 RNAi - H00083594-R01 from Novus Biologicals
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shRNA set against Human NUDT12 (NM_031438.2) - SHH356036 from Creative biogene
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shRNA set against Human NUDT12(NM_031438.2) - SHR025482 from Creative biogene
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Human NUDT12 siRNA - orb273637 from Biorbyt
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NUDT12 shRNA Plasmid (Human) - CHJ3136 from Cohesion Biosciences
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NUDT12 miRNA 3'UTR clone - MiUTR1H-06966 from Creative biogene
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