| Gene Symbol |
EIF2A
|
| Entrez Gene |
83939
|
| Alt Symbol |
CDA02, EIF-2A, MST089, MSTP004, MSTP089
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
eukaryotic translation initiation factor 2A, 65kDa
|
| Other Description |
65 kDa eukaryotic translation initiation factor 2A|eukaryotic translation initiation factor 2A
|
| Swissprots |
A8MPS6 B4DF96 B4DQ14 Q96EW9 Q7Z4E9 Q5QTR2 Q8NFM1 Q9BY44 Q96K81 D3DNI9
|
| Accessions |
EAW78830 EAW78831 EAW78832 Q9BY44 AF109358 AAQ13506 AF172818 AAQ13612 AF212241 AAK14926 AF497978 AAM83402 AI560242 AK027356 BAB55058 AK293993 BAG57357 AK298586 BAG60776 AL833101 BC011885 AAH11885 BX647951 DQ896788 ABM87787 EU176412 ABW03863 XM_011513223 XP_011511525 XM_011513224 XP_011511526 NM_032025 NP_114414
|
| Function |
Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF- 2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon- dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins. {ECO:0000269|PubMed:12133843}.
|
| Tissue Specificity |
Widely expressed. Expressed at higher level in pancreas, heart, brain and placenta. {ECO:0000269|PubMed:12133843}.
|
![Western Blot: eIF2A Overexpression Lysate (Adult Normal) [NBL1-10174] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for eIF2A.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7660_eIF2A%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10174-img0002.jpg)