| Gene Symbol |
SSTR3
|
| Entrez Gene |
6753
|
| Alt Symbol |
SS-3-R, SS3-R, SS3R, SSR-28
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
somatostatin receptor 3
|
| Other Description |
somatostatin receptor type 3
|
| Swissprots |
P32745 A8K550 Q53ZR7
|
| Accessions |
AAA60592 AAF14852 AAP32288 AAP84354 CBE74687 CDM63484 EAW60148 P32745 AK291165 BAF83854 BC042068 AAH42068 BC096829 AAH96829 BF513812 BF514979 BF515539 BU584980 CR456585 CAG30471 CU013185 CAK54616 CU013473 CAK54915 XM_005261721 XP_005261778 XM_006724311 XP_006724374 XM_011530348 XP_011528650 XM_011530349 XP_011528651 XM_011530350 XP_011528652 NM_001051 NP_001042 NM_001278687 NP_001265616
|
| Function |
Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. {ECO:0000269|PubMed:1337145}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Internalized into endoplasmic vesicles upon somatostatin-stimulation. {ECO:0000250}.
|
| Tissue Specificity |
Brain, pituitary and pancreas. {ECO:0000269|PubMed:1337145}.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|