Gene Symbol | SSTR3 |
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Entrez Gene | 6753 |
Alt Symbol | SS-3-R, SS3-R, SS3R, SSR-28 |
Species | Human |
Gene Type | protein-coding |
Description | somatostatin receptor 3 |
Other Description | somatostatin receptor type 3 |
Swissprots | P32745 A8K550 Q53ZR7 |
Accessions | AAA60592 AAF14852 AAP32288 AAP84354 CBE74687 CDM63484 EAW60148 P32745 AK291165 BAF83854 BC042068 AAH42068 BC096829 AAH96829 BF513812 BF514979 BF515539 BU584980 CR456585 CAG30471 CU013185 CAK54616 CU013473 CAK54915 XM_005261721 XP_005261778 XM_006724311 XP_006724374 XM_011530348 XP_011528650 XM_011530349 XP_011528651 XM_011530350 XP_011528652 NM_001051 NP_001042 NM_001278687 NP_001265616 |
Function | Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. {ECO:0000269|PubMed:1337145}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Internalized into endoplasmic vesicles upon somatostatin-stimulation. {ECO:0000250}. |
Tissue Specificity | Brain, pituitary and pancreas. {ECO:0000269|PubMed:1337145}. |
Top Pathways | Neuroactive ligand-receptor interaction |
SSTR3 CRISPR/Cas9 KO Plasmid (h) - sc-403411 from Santa Cruz Biotechnology
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SSTR3 HDR Plasmid (h) - sc-403411-HDR from Santa Cruz Biotechnology
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SSTR3 Double Nickase Plasmid (h) - sc-403411-NIC from Santa Cruz Biotechnology
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SSTR3 Double Nickase Plasmid (h2) - sc-403411-NIC-2 from Santa Cruz Biotechnology
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SSTR3 CRISPR Activation Plasmid (h) - sc-403411-ACT from Santa Cruz Biotechnology
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SSTR3 CRISPR Activation Plasmid (h2) - sc-403411-ACT-2 from Santa Cruz Biotechnology
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SSTR3 Lentiviral Activation Particles (h) - sc-403411-LAC from Santa Cruz Biotechnology
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SSTR3 Lentiviral Activation Particles (h2) - sc-403411-LAC-2 from Santa Cruz Biotechnology
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SSTR3 siRNA (h) - sc-42273 from Santa Cruz Biotechnology
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SSTR3 shRNA Plasmid (h) - sc-42273-SH from Santa Cruz Biotechnology
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SSTR3 shRNA (h) Lentiviral Particles - sc-42273-V from Santa Cruz Biotechnology
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Somatostatin R3/SSTR3 RNAi - H00006753-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN20636 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20636 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02600 from Sigma-Aldrich
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SSTR3 siRNA (Human) - CRH4616 from Cohesion Biosciences
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SSTR3 - MBS8208843 from MyBioSource
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shRNA set against Human SSTR3 (NM_001051.2) - SHH418592 from Creative biogene
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shRNA set against Human SSTR3(NM_001051.2) - SHL036800 from Creative biogene
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Human SSTR3 siRNA - orb265118 from Biorbyt
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SSTR3 shRNA Plasmid (Human) - CHH4616 from Cohesion Biosciences
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SSTR3 miRNA 3'UTR clone - MiUTR1H-09932 from Creative biogene
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