| Gene Symbol |
NSMAF
|
| Entrez Gene |
8439
|
| Alt Symbol |
FAN
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
neutral sphingomyelinase (N-SMase) activation associated factor
|
| Other Description |
factor associated with N-SMase activation|factor associated with neutral sphingomyelinase activation|protein FAN
|
| Swissprots |
E9PCH0 B4DFB0 Q92636 Q8IW26
|
| Accessions |
EAW86817 Q92636 AK292679 BAF85368 AK294009 BAG57371 AK313991 BAG36703 BC041124 AAH41124 DR005814 X96586 CAA65405 NM_001144772 NP_001138244 NM_003580 NP_003571
|
| Function |
Couples the p55 TNF-receptor (TNF-R55 / TNFR1) to neutral sphingomyelinase (N-SMASE). Specifically binds to the N- smase activation domain of TNF-R55. May regulate ceramide production by N-SMASE.
|
| Tissue Specificity |
Ubiquitous.
|
| Top Pathways |
Sphingolipid signaling pathway
|