| Gene Symbol |
MTPN
|
| Entrez Gene |
136319
|
| Alt Symbol |
GCDP, V-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
myotrophin
|
| Other Description |
granule cell differentiation protein|protein V-1
|
| Swissprots |
P58546
|
| Accessions |
EAL24056 EAW83859 EAW83860 P58546 AF106075 AAP97226 AK055660 AK056225 BAG51651 AK309816 AL110137 AL834231 CAD38909 AM393216 CAL38094 AM393266 CAL38144 AY611627 AAU14892 BC028093 AAH28093 BC034722 CB530008 DA325130 NM_145808 NP_665807
|
| Function |
Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity (By similarity). Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. {ECO:0000250, ECO:0000269|PubMed:10329199, ECO:0000269|PubMed:16895918, ECO:0000269|PubMed:20625546}.
|
| Subcellular Location |
Cytoplasm {ECO:0000305}. Nucleus {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:10329199}.
|