ATAT1

Gene Symbol ATAT1
Entrez Gene 79969
Alt Symbol C6orf134, MEC17, Nbla00487, TAT
Species Human
Gene Type protein-coding
Description alpha tubulin acetyltransferase 1
Other Description TAT|acetyltransferase mec-17 homolog|alpha-TAT|alpha-TAT1|alpha-tubulin N-acetyltransferase 1
Swissprots Q9BRS1 Q8NDK9 Q3LIB0 Q5SQI0 Q86X42 Q5SQI1 Q5JP39 Q9H8X5 A2AB28 Q5SU03 Q5JP40 Q5JP42
Accessions EAX03306 EAX03307 EAX03308 EAX03309 Q5SQI0 AB075512 BAE45758 AK023220 BAB14472 AK225107 AK297661 BAH12643 AK298743 BAH12864 AL535697 AL833858 CAD38717 BC006105 AAH06105 BC025755 AAH25755 BC047303 AAH47303 BX418089 BX418559 BX442806 CX786272 DB090032 XM_005249414 XP_005249471 XM_005249415 XP_005249472 XM_005249416 XP_005249473 XM_005249417 XP_005249474 XM_005249418 XP_005249475 XM_005249419 XP_005249476 XM_005249420 XP_005249477 XM_005272895 XP_005272952 XM_005272896 XP_005272953 XM_005272897 XP_005272954 XM_005272898 XP_005272955 XM_005272899 XP_005272956 XM_005272900 XP_005272957 XM_005272901 XP_005272958 XM_005275050 XP_005275107 XM_005275051 XP_005275108 XM_005275052 XP_005275109 XM_005275053 XP_005275110 XM_005275054 XP_005275111 XM_005275055 XP_005275112 XM_005275056 XP_005275113 XM_005275185 XP_005275242 XM_005275186 XP_005275243 XM_005275187 XP_005275244 XM_005275188 XP_005275245 XM_005275189 XP_005275246 XM_005275190 XP_005275247 XM_005275191 XP_005275248 XM_005275307 XP_005275364 XM_005275308 XP_005275365 XM_005275309 XP_005275366 XM_005275310 XP_005275367 XM_005275311 XP_005275368 XM_005275312 XP_005275369 XM_005275313 XP_005275370 XM_005275480 XP_005275537 XM_005275481 XP_005275538 XM_005275482 XP_005275539 XM_005275483 XP_005275540 XM_005275484 XP_005275541 XM_005275485 XP_005275542 XM_005275486 XP_005275543 XM_005275611 XP_005275668 XM_005275612 XP_005275669 XM_005275613 XP_005275670 XM_005275614 XP_005275671 XM_005275615 XP_005275672 XM_005275616 XP_005275673 XM_005275617 XP_005275674 XM_011514918 XP_011513220 XM_011547316 XP_011545618 XM_011547718 XP_011546020 XM_011547935 XP_011546237 XM_011548104 XP_011546406 XM_011548303 XP_011546605 XM_011548488 XP_011546790 XR_241917 XR_241918 XR_241919 XR_241920 XR_246968 XR_246969 XR_246970 XR_246971 XR_247355 XR_247356 XR_247357 XR_247358 XR_247376 XR_247377 XR_247378 XR_247379 XR_247391 XR_247392 XR_247393 XR_247394 XR_247407 XR_247408 XR_247409 XR_247410 XR_247428 XR_247429 XR_247430 XR_247431 XR_926309 XR_926310 XR_926311 XR_926312 XR_952215 XR_952216 XR_952217 XR_952218 XR_952667 XR_952668 XR_952669 XR_952670 XR_952859 XR_952860 XR_952862 XR_952863 XR_952950 XR_952951 XR_952952 XR_952953 XR_953011 XR_953012 XR_953013 XR_953014 XR_953084 XR_953085 XR_953086 XR_953087 NM_001190724 NR_033821 NR_033823 NM_001031722 NP_001026892 NM_001254952 NP_001241881 NM_024909 NP_079185
Function Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Required for normal sperm flagellar function. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly. {ECO:0000255|HAMAP-Rule:MF_03130, ECO:0000269|PubMed:20829795, ECO:0000269|PubMed:21068373, ECO:0000269|PubMed:24097348}.
Subcellular Location Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03130, ECO:0000269|PubMed:24097348}. Membrane, clathrin-coated pit {ECO:0000255|HAMAP-Rule:MF_03130, ECO:0000269|PubMed:24097348}. Cell junction, focal adhesion {ECO:0000255|HAMAP-Rule:MF_03130, ECO:0000269|PubMed:24097348}. Cell projection, axon {ECO:0000255|HAMAP-Rule:MF_03130}. Cytoplasm, cytoskeleton {ECO:0000255|HAMAP-Rule:MF_03130}. Cytoplasm, cytoskeleton, spindle {ECO:0000255|HAMAP-Rule:MF_03130}.

C6orf134 CRISPR/Cas9 KO Plasmid (h) - sc-403021 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C6orf134 HDR Plasmid (h) - sc-403021-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C6orf134 Double Nickase Plasmid (h) - sc-403021-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C6orf134 Double Nickase Plasmid (h2) - sc-403021-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C6orf134 CRISPR Activation Plasmid (h) - sc-403021-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C6orf134 CRISPR Activation Plasmid (h2) - sc-403021-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C6orf134 Lentiviral Activation Particles (h) - sc-403021-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C6orf134 Lentiviral Activation Particles (h2) - sc-403021-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C6orf134 siRNA (h) - sc-95272 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C6orf134 shRNA Plasmid (h) - sc-95272-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C6orf134 shRNA (h) Lentiviral Particles - sc-95272-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU153011 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3630 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3630 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ATAT1 siRNA (Human) - CRJ2699 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ATAT1 - MBS8200607 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ATAT1 (NM_024909.2) - SHH241858 from Creative biogene

Category siRNA
Species Reactivities Human

Human ATAT1 siRNA - orb273200 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ATAT1 shRNA Plasmid (Human) - CHJ2699 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ATAT1 miRNA 3'UTR clone - MiUTR3H-13678 from Creative biogene

Species Reactivities Human
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