| Gene Symbol |
ADAM9
|
| Entrez Gene |
8754
|
| Alt Symbol |
CORD9, MCMP, MDC9, Mltng
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ADAM metallopeptidase domain 9
|
| Other Description |
ADAM metallopeptidase domain 9 (meltrin gamma)|cellular disintegrin-related protein|cone rod dystrophy 9|disintegrin and metalloproteinase domain-containing protein 9|metalloprotease/disintegrin/cysteine-rich protein 9|myeloma cell metalloproteinase
|
| Swissprots |
Q8NFM6 Q10718 B7ZLN7 Q13443
|
| Accessions |
EAW63283 EAW63284 EAW63285 Q13443 AF495383 AAM49575 AK293257 BAG56789 AV708278 BC027996 BC126406 AAI26407 BC143923 AAI43924 BC143924 D14665 BAA03499 U41766 AAC50403 XM_011544682 XP_011542984 XR_949497 NM_003816 NP_003807 NR_027638 NR_027639 NR_027878 NM_001005845
|
| Function |
Probable zinc protease. May mediate cell-cell or cell- matrix interactions. Isoform 2 displays alpha-secretase activity for APP. {ECO:0000269|PubMed:12054541}.
|
| Subcellular Location |
Isoform 1: Cell membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Widely expressed. Expressed in chondrocytes. Isoform 2 is highly expressed in liver and heart. {ECO:0000269|PubMed:12054541, ECO:0000269|PubMed:7584026, ECO:0000269|PubMed:8647900, ECO:0000269|PubMed:9016778}.
|