Gene Symbol | ADAM9 |
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Entrez Gene | 8754 |
Alt Symbol | CORD9, MCMP, MDC9, Mltng |
Species | Human |
Gene Type | protein-coding |
Description | ADAM metallopeptidase domain 9 |
Other Description | ADAM metallopeptidase domain 9 (meltrin gamma)|cellular disintegrin-related protein|cone rod dystrophy 9|disintegrin and metalloproteinase domain-containing protein 9|metalloprotease/disintegrin/cysteine-rich protein 9|myeloma cell metalloproteinase |
Swissprots | Q8NFM6 Q10718 B7ZLN7 Q13443 |
Accessions | EAW63283 EAW63284 EAW63285 Q13443 AF495383 AAM49575 AK293257 BAG56789 AV708278 BC027996 BC126406 AAI26407 BC143923 AAI43924 BC143924 D14665 BAA03499 U41766 AAC50403 XM_011544682 XP_011542984 XR_949497 NM_003816 NP_003807 NR_027638 NR_027639 NR_027878 NM_001005845 |
Function | Probable zinc protease. May mediate cell-cell or cell- matrix interactions. Isoform 2 displays alpha-secretase activity for APP. {ECO:0000269|PubMed:12054541}. |
Subcellular Location | Isoform 1: Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Widely expressed. Expressed in chondrocytes. Isoform 2 is highly expressed in liver and heart. {ECO:0000269|PubMed:12054541, ECO:0000269|PubMed:7584026, ECO:0000269|PubMed:8647900, ECO:0000269|PubMed:9016778}. |
SignalSilence ® ADAM9 siRNA I - 11968 from Cell Signaling Technology
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SignalSilence ® ADAM9 siRNA II - 12085 from Cell Signaling Technology
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ADAM9 CRISPR/Cas9 KO Plasmid (h) - sc-403665 from Santa Cruz Biotechnology
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ADAM9 HDR Plasmid (h) - sc-403665-HDR from Santa Cruz Biotechnology
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ADAM9 Double Nickase Plasmid (h) - sc-403665-NIC from Santa Cruz Biotechnology
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ADAM9 Double Nickase Plasmid (h2) - sc-403665-NIC-2 from Santa Cruz Biotechnology
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ADAM9 CRISPR Activation Plasmid (h) - sc-403665-ACT from Santa Cruz Biotechnology
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ADAM9 CRISPR Activation Plasmid (h2) - sc-403665-ACT-2 from Santa Cruz Biotechnology
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ADAM9 Lentiviral Activation Particles (h) - sc-403665-LAC from Santa Cruz Biotechnology
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ADAM9 Lentiviral Activation Particles (h2) - sc-403665-LAC-2 from Santa Cruz Biotechnology
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ADAM9 siRNA (h) - sc-41408 from Santa Cruz Biotechnology
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ADAM9 shRNA Plasmid (h) - sc-41408-SH from Santa Cruz Biotechnology
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ADAM9 shRNA (h) Lentiviral Particles - sc-41408-V from Santa Cruz Biotechnology
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ADAM9 RNAi - H00008754-R01 from Novus Biologicals
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ADAM9 RNAi - H00008754-R02 from Novus Biologicals
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MISSION® esiRNA - EHU020151 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2178 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2178 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10034 from Sigma-Aldrich
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ADAM9 siRNA (Human) - CRH5768 from Cohesion Biosciences
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ADAM9 - MBS8219613 from MyBioSource
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shRNA set against Human Adam9 (NM_003816.2) - SHH231702 from Creative biogene
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shRNA set against Human ADAM9(NM_003816.2) - SHG039319 from Creative biogene
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Human ADAM9 siRNA - orb266270 from Biorbyt
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ADAM9 shRNA Plasmid (Human) - CHH5768 from Cohesion Biosciences
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