Gene Symbol | DIXDC1 |
---|---|
Entrez Gene | 85458 |
Alt Symbol | CCD1 |
Species | Human |
Gene Type | protein-coding |
Description | DIX domain containing 1 |
Other Description | coiled-coil protein DIX1|dixin |
Swissprots | Q96N69 E9PRV4 Q8IVY4 Q155Q3 Q9C0C8 A1A5D8 Q6PIK4 Q86SR7 Q6P2J8 |
Accessions | EAW67171 EAW67172 EAW67173 Q155Q3 AB051522 BAB21826 AB074187 AF070621 AK055469 BAG51522 AK055899 BAB71039 AK074277 AK289807 BAF82496 AK294954 BAG58029 AU253693 BC033034 AAH33034 BC035509 AAH35509 BC041626 AAH41626 BC048294 AAH48294 BC064479 AAH64479 BC128600 AAI28601 BX370159 DA096120 DB358954 DB459100 DQ642016 ABG25914 HY037299 XM_005277726 XP_005277783 XM_005277727 XP_005277784 XM_005277728 XP_005277785 XM_011543045 XP_011541347 XM_011543046 XP_011541348 NM_001037954 NP_001033043 NM_001278542 NP_001265471 NM_033425 NP_219493 |
Function | Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2. {ECO:0000269|PubMed:15262978, ECO:0000269|PubMed:21189423}. |
Subcellular Location | Isoform 2: Cytoplasm. |
Tissue Specificity | Ubiquitously expressed with higher expression in cardiac and skeletal muscles. {ECO:0000269|PubMed:16814745}. |