KCNJ4

Gene Symbol	KCNJ4
Entrez Gene	3761
Alt Symbol	HIR, HIRK2, HRK1, IRK-3, IRK3, Kir2.3
Species	Human
Gene Type	protein-coding
Description	potassium channel, inwardly rectifying subfamily J, member 4
Other Description	hippocampal inward rectifier potassium channel|inward rectifier K(+) channel Kir2.3|inward rectifier K+ channel Kir2.3|inward rectifier potassium channel 4|potassium channel, inwardly rectifying subfamily J member 4|potassium inwardly-rectifying channel, subfamily J, member 4
Swissprots	P48050 Q14D44
Accessions	EAW60235 EAW60236 P48050 BC032562 AAH32562 BC039618 BC113506 AAI13507 BC113508 AAI13509 BM475496 CR456507 CAG30393 CU013106 CAK54537 CU013394 CAK54836 S72503 AAC60632 U07364 AAA19962 U24056 AAA66076 NM_004981 NP_004972 NM_152868 NP_690607
Function	Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}. Note=TAX1BP3 binding promotes dissociation of KCNJ4 from LIN7 famaly members and KCNJ4 internalization. {ECO:0000250}.
Tissue Specificity	Heart, skeletal muscle, and several different brain regions including the hippocampus.
Top Pathways	Oxytocin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

KIR2.3 (S-22) - sc-23632 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-KIR2.3 antibody - ab110701 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KIR2.3 antibody [S25-35] - ab84822 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S25-35

Anti-KIR2.3 antibody - N-terminal - ab170663 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-KCNJ4 / Kir2.3 Antibody (clone S25-35) - LS-C152677 from LifeSpan Bioscience Prices $415.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S25-35

Anti-KCNJ4 / Kir2.3 Antibody (Glu285) - LS-C193176 from LifeSpan Bioscience Prices $385.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KCNJ4 / Kir2.3 Antibody (aa390-445, clone S25-35, Atto 565) - LS-C230722 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S25-35

Anti-KCNJ4 / Kir2.3 Antibody (aa390-445, clone S25-35, Atto 594) - LS-C230723 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S25-35

Anti-KCNJ4 / Kir2.3 Antibody (C-Terminus) - LS-C110000 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-KCNJ4 / Kir2.3 Antibody (aa390-445) IHC-plus™ - LS-B6727 from LifeSpan Bioscience Prices $395.00 Sizes 50 µg Host Mouse Clonality Monoclonal

Anti-KCNJ4 / Kir2.3 Antibody (aa390-445, clone S25-35, Atto 655) - LS-C230725 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S25-35

Anti-KCNJ4 / Kir2.3 Antibody (aa390-445, clone S25-35, Atto 633) - LS-C230724 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S25-35

Anti-KCNJ4 / Kir2.3 Antibody (aa390-445, clone S25-35, Atto 700) - LS-C230727 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S25-35

Anti-KCNJ4 / Kir2.3 Antibody (aa390-445, clone S25-35, Atto 680) - LS-C230726 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S25-35

Anti-KCNJ4 / Kir2.3 Antibody (aa390-445, clone S25-35, AP) - LS-C230728 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S25-35

Anti-KCNJ4 / Kir2.3 Antibody (aa390-445, clone S25-35, APC) - LS-C230729 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S25-35

Anti-KCNJ4 / Kir2.3 Antibody (aa1-30) - LS-C165434 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-KCNJ4 / Kir2.3 Antibody (aa390-445, clone S25-35, Biotin) - LS-C230730 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S25-35

Anti-KCNJ4 / Kir2.3 Antibody (aa390-445, clone S25-35, FITC) - LS-C230731 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S25-35

Anti-KCNJ4 / Kir2.3 Antibody (aa390-445, clone S25-35, PE, Atto 594) - LS-C230733 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S25-35

Anti-KCNJ4 / Kir2.3 Antibody (aa390-445, clone S25-35, PerCP) - LS-C230734 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S25-35

Anti-KCNJ4 / Kir2.3 Antibody (aa390-445, clone S25-35, RPE) - LS-C230735 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S25-35

Anti-KCNJ4 / Kir2.3 Antibody (aa390-445, clone S25-35, SA) - LS-C230737 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S25-35

Anti-KCNJ4 / Kir2.3 Antibody (aa390-445, clone S25-35, Atto 390) - LS-C230994 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S25-35

Anti-KCNJ4 / Kir2.3 Antibody (aa1-30, APC) - LS-C260942 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

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