GRM2

Gene Symbol	GRM2
Entrez Gene	2912
Alt Symbol	GLUR2, GPRC1B, MGLUR2, mGlu2
Species	Human
Gene Type	protein-coding
Description	glutamate receptor, metabotropic 2
Other Description	glutamate metabotropic receptor 2|glutamate receptor homolog|metabotropic glutamate receptor 2
Swissprots	Q52MC6 Q14CU5 Q9H3N6 B0M0K7 Q14416
Accessions	BAB19817 EAW65150 Q14416 AB209164 BAD92401 AK289984 BAF82673 AK302671 BAG63904 AK313056 AK315816 BAF98707 AY999299 AAY14640 BC041447 AAH41447 BC113615 AAI13616 BC113619 AAI13620 BX648951 DA391442 EU432122 ABY87921 HQ258674 ADR83425 L35318 AAA76855 XM_011533635 XP_011531937 XM_011533636 XP_011531938 XM_011533637 XP_011531939 XM_011533638 XP_011531940 XM_011533639 XP_011531941 XM_011533640 XP_011531942 XM_011533641 XP_011531943 XM_011533642 XP_011531944 XM_011533643 XP_011531945 XM_011533644 XP_011531946 XM_011533645 XP_011531947 XM_011533646 XP_011531948 XM_011533647 XP_011531949 XR_940421 NM_000839 NP_000830 NM_001130063 NP_001123535
Function	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization. {ECO:0000269|PubMed:18297054, ECO:0000269|PubMed:22300836, ECO:0000269|PubMed:23129762, ECO:0000269|PubMed:7620613}.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Cell junction, synapse {ECO:0000250}. Cell projection, dendrite {ECO:0000250}.
Tissue Specificity	Detected in brain cortex (at protein level). Widely expressed in different regions of the adult brain as well as in fetal brain. {ECO:0000269|PubMed:18297054}.
Top Pathways	Glutamatergic synapse, Cocaine addiction, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Metabotropic Glutamate Receptor 2 full length protein - ab158587 from Abcam Category Protein Source Wheat germ Species Human

Human Metabotropic Glutamate Receptor 2 protein fragment - ab158588 from Abcam Category Protein Source Wheat germ Species Human

GRM2 / MGLUR2 Antibody Blocking Peptide - LS-E27429 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GRM2 / MGLUR2 Antibody Blocking Peptide - LS-E29515 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GRM2 / MGLUR2 Antibody Blocking Peptide - LS-E29528 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GRM2 / MGLUR2 Antibody Blocking Peptide - LS-E29176 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GRM2 / MGLUR2 Antibody Blocking Peptide - LS-E29175 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

mGluR2 Recombinant Protein - H00002912-P01 from Novus Biologicals Category Protein Species Human

Recombinant Human mGluR2 Protein - H00002912-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

mGluR2 Recombinant Protein - H00002912-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

GLUR2 Blocking Peptide - abx062695 from Abbexa Category Peptide Species Human, Mouse, Rat, Chicken, Monkey, Zebrafish

mGLUR2 Blocking Peptide - abx062698 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey

Metabotropic Glutamate Receptor 2 Peptide - AC21-2252-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

mGluR2 / GRM2 - H00002912-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

mGluR2 / GRM2 - H00002912-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

mGluR2 / GRM2 - H00002912-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

mGluR2/3, control peptide - 214-10020 from RayBiotech Category Peptide

GRM2 Peptide - 42-627P from ProSci Category Peptide Species Human

ChemiSCREEN™ Human Recombinant mGlu 2 Metabotropic Glutamate Receptor Calcium-Optimized Stable Cell Line - HTS146C from EMD Millipore Species Human

mGLUR2 Blocking Peptide - CBP1504 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Monkey

mGluR-2/3 (N867)Peptide - BS3430P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) - RPE802Hu01 from Cloud-clone Category Protein Source E.coli Species Human

GRM2, Peptide - MBS427664 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Bovine, Rabbit

ChemiSCREEN™ Membrane Preparation Recombinant Human mGLU 2 Metabotropic Glutamate Receptor - HTS146M from EMD Millipore Prices $905.00 Sizes 200 units Species Human

mGluR2 Recombinant Protein Antigen - NBP2-49436PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

Search more