Gene Symbol |
IMPAD1
|
Entrez Gene |
54928
|
Alt Symbol |
GPAPP, IMP 3, IMP-3, IMPA3
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
inositol monophosphatase domain containing 1
|
Other Description |
Golgi 3-prime phosphoadenosine 5-prime phosphate 3-prime phosphatase|IMPase 3|golgi-resident PAP phosphatase|inositol monophosphatase 3|inositol monophosphatase domain-containing protein 1|inositol-1(or 4)-monophosphatase 3|myo-inositol monophosphatase A3
|
Swissprots |
Q6NVY7 Q9NX62
|
Accessions |
EAW86789 EAW86790 EAW86791 Q9NX62 AI095394 AK000428 BAA91158 AK090988 BAC03563 AY032885 AAK52336 BC017797 AAH17797 BC067814 AAH67814 BI601447 XR_928786 NM_017813 NP_060283
|
Function |
May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. {ECO:0000250}.
|
Subcellular Location |
Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:18695242}; Single-pass type II membrane protein {ECO:0000269|PubMed:18695242}.
|
Top Pathways |
Sulfur metabolism, Inositol phosphate metabolism, Phosphatidylinositol signaling system
|