Gene Symbol | IMPAD1 |
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Entrez Gene | 54928 |
Alt Symbol | GPAPP, IMP 3, IMP-3, IMPA3 |
Species | Human |
Gene Type | protein-coding |
Description | inositol monophosphatase domain containing 1 |
Other Description | Golgi 3-prime phosphoadenosine 5-prime phosphate 3-prime phosphatase|IMPase 3|golgi-resident PAP phosphatase|inositol monophosphatase 3|inositol monophosphatase domain-containing protein 1|inositol-1(or 4)-monophosphatase 3|myo-inositol monophosphatase A3 |
Swissprots | Q6NVY7 Q9NX62 |
Accessions | EAW86789 EAW86790 EAW86791 Q9NX62 AI095394 AK000428 BAA91158 AK090988 BAC03563 AY032885 AAK52336 BC017797 AAH17797 BC067814 AAH67814 BI601447 XR_928786 NM_017813 NP_060283 |
Function | May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. {ECO:0000250}. |
Subcellular Location | Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:18695242}; Single-pass type II membrane protein {ECO:0000269|PubMed:18695242}. |
Top Pathways | Sulfur metabolism, Inositol phosphate metabolism, Phosphatidylinositol signaling system |
IMPA3 CRISPR/Cas9 KO Plasmid (h) - sc-412384 from Santa Cruz Biotechnology
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IMPA3 HDR Plasmid (h) - sc-412384-HDR from Santa Cruz Biotechnology
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IMPA3 Double Nickase Plasmid (h) - sc-412384-NIC from Santa Cruz Biotechnology
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IMPA3 Double Nickase Plasmid (h2) - sc-412384-NIC-2 from Santa Cruz Biotechnology
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IMPA3 CRISPR Activation Plasmid (h) - sc-412384-ACT from Santa Cruz Biotechnology
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IMPA3 CRISPR Activation Plasmid (h2) - sc-412384-ACT-2 from Santa Cruz Biotechnology
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IMPA3 Lentiviral Activation Particles (h) - sc-412384-LAC from Santa Cruz Biotechnology
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IMPA3 Lentiviral Activation Particles (h2) - sc-412384-LAC-2 from Santa Cruz Biotechnology
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IMPA3 siRNA (h) - sc-77647 from Santa Cruz Biotechnology
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IMPA3 shRNA Plasmid (h) - sc-77647-SH from Santa Cruz Biotechnology
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IMPA3 shRNA (h) Lentiviral Particles - sc-77647-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU048561 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0257 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0256 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0258 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10659 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10659 from Sigma-Aldrich
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IMPAD1 siRNA (Human) - CRJ0331 from Cohesion Biosciences
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IMPAD1 - MBS829947 from MyBioSource
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shRNA set against Human IMPAD1 (NM_017813.4) - SHH319337 from Creative biogene
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IMPAD1 shRNA Plasmid (Human) - CHJ0331 from Cohesion Biosciences
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