Gene Symbol |
GATA6
|
Entrez Gene |
2627
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
GATA binding protein 6
|
Other Description |
GATA-binding factor 6|transcription factor GATA-6
|
Swissprots |
Q92908 P78327 B0YJ17
|
Accessions |
ACA05995 EAX01137 Q92908 AK223547 BAD97267 AU309820 BC027891 AAH27891 CN280495 D87811 BAA22621 HY052912 N91601 U66075 AAC50941 W19304 X95701 CAA64997 NM_005257 NP_005248
|
Function |
Transcriptional activator that regulates SEMA3C and PLXNA2. Thought to be important for regulating terminal differentiation and/or proliferation. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity). {ECO:0000250}.
|
Subcellular Location |
Nucleus {ECO:0000269|PubMed:19666519}.
|
Tissue Specificity |
Expressed in heart, gut and gut-derived tissues.
|