Gene Symbol | GATA6 |
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Entrez Gene | 2627 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | GATA binding protein 6 |
Other Description | GATA-binding factor 6|transcription factor GATA-6 |
Swissprots | Q92908 P78327 B0YJ17 |
Accessions | ACA05995 EAX01137 Q92908 AK223547 BAD97267 AU309820 BC027891 AAH27891 CN280495 D87811 BAA22621 HY052912 N91601 U66075 AAC50941 W19304 X95701 CAA64997 NM_005257 NP_005248 |
Function | Transcriptional activator that regulates SEMA3C and PLXNA2. Thought to be important for regulating terminal differentiation and/or proliferation. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:19666519}. |
Tissue Specificity | Expressed in heart, gut and gut-derived tissues. |
GATA-6 CRISPR/Cas9 KO Plasmid (h) - sc-400724 from Santa Cruz Biotechnology
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GATA-6 HDR Plasmid (h) - sc-400724-HDR from Santa Cruz Biotechnology
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GATA-6 Double Nickase Plasmid (h) - sc-400724-NIC from Santa Cruz Biotechnology
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GATA-6 Double Nickase Plasmid (h2) - sc-400724-NIC-2 from Santa Cruz Biotechnology
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GATA-6 CRISPR Activation Plasmid (h) - sc-400724-ACT from Santa Cruz Biotechnology
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GATA-6 CRISPR Activation Plasmid (h2) - sc-400724-ACT-2 from Santa Cruz Biotechnology
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GATA-6 Lentiviral Activation Particles (h) - sc-400724-LAC from Santa Cruz Biotechnology
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GATA-6 Lentiviral Activation Particles (h2) - sc-400724-LAC-2 from Santa Cruz Biotechnology
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GATA-6 siRNA (h) - sc-37907 from Santa Cruz Biotechnology
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GATA-6 shRNA Plasmid (h) - sc-37907-SH from Santa Cruz Biotechnology
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GATA-6 shRNA (h) Lentiviral Particles - sc-37907-V from Santa Cruz Biotechnology
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GATA-6 RNAi - H00002627-R01 from Novus Biologicals
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MISSION® esiRNA - EHU129811 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9151 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9151 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09592 from Sigma-Aldrich
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GATA6 siRNA (Human) - CRH1743 from Cohesion Biosciences
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GATA6 - MBS8218295 from MyBioSource
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GATA-6 CRISPR/Cas9 KO Plasmid (h2) - sc-400724-KO-2 from Santa Cruz Biotechnology
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GATA-6 HDR Plasmid (h2) - sc-400724-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human GATA6 (NM_005257.4) - SHH299582 from Creative biogene
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GATA6 shRNA Plasmid (Human) - CHH1743 from Cohesion Biosciences
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GATA6 miRNA 3'UTR clone - MiUTR3H-04294 from Creative biogene
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