| Gene Symbol |
PTBP3
|
| Entrez Gene |
9991
|
| Alt Symbol |
ROD1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
polypyrimidine tract binding protein 3
|
| Other Description |
ROD1 regulator of differentiation 1|fission yeast differentiation regulator|polypyrimidine tract-binding protein 3|regulator of differentiation 1
|
| Swissprots |
B1ALY6 Q68DB9 B1ALY5 B1ALY2 B3KME7 Q86YB3 Q86YH9 O95758 B1ALY3
|
| Accessions |
EAW59099 EAW59100 EAW59101 EAW59102 O95758 AB023967 BAA75466 AK001685 BAG50959 AK302558 BAG63824 AL710523 BC039896 AAH39896 BC044585 AAH44585 BC045825 BI463123 BQ006891 BX097575 BX422279 CN371677 CR749471 CAH18301 XM_005252324 XP_005252381 XM_006717343 XP_006717406 XM_006717346 XP_006717409 XM_011519265 XP_011517567 XM_011519266 XP_011517568 XM_011519267 XP_011517569 NM_001163788 NP_001157260 NM_001163790 NP_001157262 NM_001244896 NP_001231825 NM_001244897 NP_001231826 NM_001244898 NP_001231827 NM_005156 NP_005147
|
| Function |
RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U). {ECO:0000269|PubMed:10207106, ECO:0000269|PubMed:18335065, ECO:0000269|PubMed:19441079, ECO:0000269|PubMed:20937273}.
|
| Tissue Specificity |
Expressed in several hematopoietic cell lines examined. {ECO:0000269|PubMed:10207106}.
|
![Western Blot: ROD1 Overexpression Lysate (Adult Normal) [NBP2-10152] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ROD1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10586_ROD1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10152-img0001.jpg)