Gene Symbol |
DBP
|
Entrez Gene |
1628
|
Alt Symbol |
DABP
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
D site of albumin promoter (albumin D-box) binding protein
|
Other Description |
D site-binding protein|albumin D box-binding protein|albumin D-element-binding protein|tax-responsive enhancer element-binding protein 302|taxREB302
|
Swissprots |
A2I2P4 Q10586
|
Accessions |
AAB18668 ABM64213 EAW52372 EAW52373 EAW52374 EAW52375 Q10586 AB208807 BAD92044 AK310025 BC011965 AAH11965 BT006836 AAP35482 CA425431 D28468 BAA05833 DA068934 DT217864 U06936 AAA81374 U79283 AAB50219 XR_243907 NM_001352 NP_001343
|
Function |
This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation.
|
Subcellular Location |
Nucleus.
|
Tissue Specificity |
Ubiquitously expressed. Expressed in the suprachiasmatic nuclei (SCN) and in most peripheral tissues, with a strong circadian rhythmicity.
|