Gene Symbol | DBP |
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Entrez Gene | 1628 |
Alt Symbol | DABP |
Species | Human |
Gene Type | protein-coding |
Description | D site of albumin promoter (albumin D-box) binding protein |
Other Description | D site-binding protein|albumin D box-binding protein|albumin D-element-binding protein|tax-responsive enhancer element-binding protein 302|taxREB302 |
Swissprots | A2I2P4 Q10586 |
Accessions | AAB18668 ABM64213 EAW52372 EAW52373 EAW52374 EAW52375 Q10586 AB208807 BAD92044 AK310025 BC011965 AAH11965 BT006836 AAP35482 CA425431 D28468 BAA05833 DA068934 DT217864 U06936 AAA81374 U79283 AAB50219 XR_243907 NM_001352 NP_001343 |
Function | This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation. |
Subcellular Location | Nucleus. |
Tissue Specificity | Ubiquitously expressed. Expressed in the suprachiasmatic nuclei (SCN) and in most peripheral tissues, with a strong circadian rhythmicity. |
DABP CRISPR/Cas9 KO Plasmid (h) - sc-405222 from Santa Cruz Biotechnology
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DABP HDR Plasmid (h) - sc-405222-HDR from Santa Cruz Biotechnology
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DABP Double Nickase Plasmid (h) - sc-405222-NIC from Santa Cruz Biotechnology
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DABP Double Nickase Plasmid (h2) - sc-405222-NIC-2 from Santa Cruz Biotechnology
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DABP CRISPR Activation Plasmid (h) - sc-405222-ACT from Santa Cruz Biotechnology
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DABP CRISPR Activation Plasmid (h2) - sc-405222-ACT-2 from Santa Cruz Biotechnology
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DABP Lentiviral Activation Particles (h) - sc-405222-LAC from Santa Cruz Biotechnology
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DABP Lentiviral Activation Particles (h2) - sc-405222-LAC-2 from Santa Cruz Biotechnology
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DABP siRNA (h) - sc-97554 from Santa Cruz Biotechnology
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DABP shRNA Plasmid (h) - sc-97554-SH from Santa Cruz Biotechnology
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DABP shRNA (h) Lentiviral Particles - sc-97554-V from Santa Cruz Biotechnology
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D Box Binding Protein RNAi - H00001628-R01 from Novus Biologicals
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MISSION® esiRNA - EHU143821 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6952 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6952 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00435 from Sigma-Aldrich
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DBP siRNA (Human) - CRH1145 from Cohesion Biosciences
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DBP - MBS8225987 from MyBioSource
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DABP CRISPR/Cas9 KO Plasmid (h2) - sc-405222-KO-2 from Santa Cruz Biotechnology
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DABP HDR Plasmid (h2) - sc-405222-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human DBP (NM_001352.3) - SHH274793 from Creative biogene
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Human DBP siRNA - orb261647 from Biorbyt
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DBP shRNA Plasmid (Human) - CHH1145 from Cohesion Biosciences
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DBP miRNA 3'UTR clone - MiUTR3H-00630 from Creative biogene
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