| Gene Symbol |
RNF170
|
| Entrez Gene |
81790
|
| Alt Symbol |
ADSA, SNAX1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ring finger protein 170
|
| Other Description |
E3 ubiquitin-protein ligase RNF170|putative LAG1-interacting protein
|
| Swissprots |
Q8N5G9 Q8N2B5 E9PIL4 Q86YC0 Q8IXR7 Q9H0V6 D3DSY6 Q96K19 Q8NG30 Q7Z483
|
| Accessions |
CAI93421 EAW63201 EAW63202 EAW63203 EAW63204 Q96K19 AA973979 AF209504 AAM92891 AK027748 BAB55340 AK090864 BAC03534 AK095625 AK225086 AK225568 AL136620 CAB66555 BC013422 AAH13422 BC032393 AAH32393 BC039461 AAH39461 BC044566 AAH44566 BC058289 BG910500 DA751961 DQ586731 EU832307 ACE87564 EU832391 ACE86876 XM_006716404 XP_006716467 XM_006716405 XP_006716468 XM_006716406 XP_006716469 XM_006716407 XP_006716470 XM_011544666 XP_011542968 XR_949487 NM_001160223 NP_001153695 NM_001160224 NP_001153696 NM_001160225 NP_001153697 NM_030954 NP_112216 NR_027668 NR_027669
|
| Function |
E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells. {ECO:0000269|PubMed:21610068}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Expressed in the spinal chord. {ECO:0000269|PubMed:21115467}.
|