| Gene Symbol |
ADAMTS20
|
| Entrez Gene |
80070
|
| Alt Symbol |
ADAM-TS20, ADAMTS-20, GON-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ADAM metallopeptidase with thrombospondin type 1 motif, 20
|
| Other Description |
A disintegrin and metalloproteinase with thrombospondin motifs 20|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 20
|
| Swissprots |
P59510 J3QT00 A6NNC9
|
| Accessions |
CCO13670 EAW57861 EAW57862 EAW57863 EAW57864 P59510 AF488804 AAO15766 AJ515153 CAD56159 AJ515154 CAD56160 AK023228 BAB14479 XM_011538754 XP_011537056 XM_011538755 XP_011537057 NM_025003 NP_079279 NM_175851
|
| Function |
May play a role in tissue-remodeling process occurring in both normal and pathological conditions. May have a protease- independent function in the transport from the endoplasmic reticulum to the Golgi apparatus of secretory cargos, mediated by the GON domain.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000250}.
|
| Tissue Specificity |
Very sparingly expressed, although is detected at low levels in testis, prostate, ovary, heart, placenta, lung and pancreas. Overexpressed in several brain, colon and breast carcinomas.
|