Gene Symbol | ADAMTS20 |
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Entrez Gene | 80070 |
Alt Symbol | ADAM-TS20, ADAMTS-20, GON-1 |
Species | Human |
Gene Type | protein-coding |
Description | ADAM metallopeptidase with thrombospondin type 1 motif, 20 |
Other Description | A disintegrin and metalloproteinase with thrombospondin motifs 20|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 20 |
Swissprots | P59510 J3QT00 A6NNC9 |
Accessions | CCO13670 EAW57861 EAW57862 EAW57863 EAW57864 P59510 AF488804 AAO15766 AJ515153 CAD56159 AJ515154 CAD56160 AK023228 BAB14479 XM_011538754 XP_011537056 XM_011538755 XP_011537057 NM_025003 NP_079279 NM_175851 |
Function | May play a role in tissue-remodeling process occurring in both normal and pathological conditions. May have a protease- independent function in the transport from the endoplasmic reticulum to the Golgi apparatus of secretory cargos, mediated by the GON domain. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
Tissue Specificity | Very sparingly expressed, although is detected at low levels in testis, prostate, ovary, heart, placenta, lung and pancreas. Overexpressed in several brain, colon and breast carcinomas. |
ADAMTS-20 CRISPR/Cas9 KO Plasmid (h) - sc-413332 from Santa Cruz Biotechnology
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ADAMTS-20 HDR Plasmid (h) - sc-413332-HDR from Santa Cruz Biotechnology
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ADAMTS-20 Double Nickase Plasmid (h) - sc-413332-NIC from Santa Cruz Biotechnology
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ADAMTS-20 Double Nickase Plasmid (h2) - sc-413332-NIC-2 from Santa Cruz Biotechnology
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ADAMTS-20 CRISPR Activation Plasmid (h) - sc-413332-ACT from Santa Cruz Biotechnology
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ADAMTS-20 CRISPR Activation Plasmid (h2) - sc-413332-ACT-2 from Santa Cruz Biotechnology
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ADAMTS-20 Lentiviral Activation Particles (h) - sc-413332-LAC from Santa Cruz Biotechnology
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ADAMTS-20 Lentiviral Activation Particles (h2) - sc-413332-LAC-2 from Santa Cruz Biotechnology
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ADAMTS-20 siRNA (h) - sc-95991 from Santa Cruz Biotechnology
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ADAMTS-20 shRNA Plasmid (h) - sc-95991-SH from Santa Cruz Biotechnology
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ADAMTS-20 shRNA (h) Lentiviral Particles - sc-95991-V from Santa Cruz Biotechnology
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ADAMTS20 RNAi - H00080070-R02 from Novus Biologicals
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ADAMTS20 RNAi - H00080070-R01 from Novus Biologicals
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MISSION® esiRNA - EHU074731 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2833 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2833 from Sigma-Aldrich
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ADAMTS20 siRNA (Human) - CRJ2745 from Cohesion Biosciences
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ADAMTS20 - MBS8215397 from MyBioSource
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shRNA set against Human Adamts20 (NM_025003.3) - SHH231854 from Creative biogene
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Human ADAMTS20 siRNA - orb273246 from Biorbyt
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ADAMTS20 shRNA Plasmid (Human) - CHJ2745 from Cohesion Biosciences
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ADAMTS20 miRNA 3'UTR clone - MiUTR1H-00173 from Creative biogene
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