Pdxp

Gene Symbol Pdxp
Entrez Gene 57028
Alt Symbol 1600027H05Rik, AB041662, PLPP
Species Mouse
Gene Type protein-coding
Description pyridoxal (pyridoxine, vitamin B6) phosphatase
Other Description PLP phosphatase|PLP-phosophatase|chronophilin|chronophin|pyridoxal phosphate phosphatase
Swissprots P60487
Accessions P60487 AB041662 BAA95107 AI845716 AI852697 AK043228 AK212826 AY366300 AAR12209 BC037010 AAH37010 BC046955 BC049107 BC058388 AAH58388 BC069982 AAH69982 BU148105 BY060098 CX236940 NM_020271 NP_064667
Function Protein serine phosphatase that dephosphorylates 'Ser-3' in cofilin and probably also dephosphorylates phospho-serine residues in DSTN. Regulates cofilin-dependent actin cytoskeleton reorganization. Required for normal progress through mitosis and normal cytokinesis (By similarity). Does not dephosphorylate phospho-threonines in LIMK1. Does not dephosphorylate peptides containing phospho-tyrosine. Pyridoxal phosphate phosphatase. Has some activity towards pyridoxal 5'-phosphate (PLP), pyridoxine 5'- phosphate (PMP) and pyridoxine 5'-phosphate (PNP), with a highest activity with PLP followed by PNP. {ECO:0000250, ECO:0000269|PubMed:24338687, ECO:0000269|Ref.4}.
Subcellular Location Cytoplasm, cytosol {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection, ruffle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell projection, lamellipodium membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Colocalizes with the actin cytoskeleton in membrane ruffles and lamellipodia. Diffusely distributed throughout the cytosol during pro-metaphase and metaphase. Detected at the dynamic cell poles during telophase. Detected at the cleavage furrow and contractile ring during cytokinesis. Transiently detected at the plasma membrane in late stages of cytokinesis. Detected at the midbody (By similarity). {ECO:0000250}.
Tissue Specificity Ubiquitous. highly expressed in brain (at protein level). {ECO:0000269|Ref.4}.
Top Pathways Vitamin B6 metabolism

Recombinant Mouse Pyridoxal phosphate phosphatase(Pdxp) - CSB-YP017749MO CSB-EP017749MO CSB-BP017749MO CSB-MP017749MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Recombinant Mouse PDXP Protein - PDXP-12604M from Creative Biomart

Category Protein
Source Mammalian Cells
Species Mouse

Recombinant Mouse Pyridoxal phosphate phosphatase(Pdxp) - RPC20351 from Biomatik

Category Protein
Prices $106.00, $242.00, $380.00, $594.00, $945.00, $1,424.00
Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg
Source E.coli
Species Mouse

Recombinant Mouse Pyridoxal phosphate phosphatase(Pdxp) - AP73984 from Signalway Antibody

Category Protein
Prices $105.00, $260.00, $454.00, $735.00, $1,240.00, $1,980.00
Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg
Source E.coli
Species Mouse

Pyridoxal phosphate phosphatase (Pdxp), Recombinant Protein - MBS9423564 from MyBioSource

Category Protein
Prices $165.00, $280.00, $435.00, $665.00, $1,080.00
Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg
Source E Coli
Species Mouse

Pyridoxal phosphate phosphatase (Pdxp), Recombinant Protein - MBS949456 from MyBioSource

Category Protein
Prices $305.00, $580.00, $950.00, $1,050.00, $1,280.00, $1,280.00, $1,390.00, $1,630.00, $2,095.00, $2,095.00
Sizes 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse

PDXP Recombinant Protein (Mouse) (OPCA04377) - OPCA04377 from Aviva Systems Biology

Category Protein
Species Mouse

Recombinant Mouse Pyridoxal phosphate phosphatase (Pdxp) - RPC24870 from Biomatik

Category Protein
Prices $332.00, $606.00, $2,989.00
Sizes 50 µg, 100 µg, 1 mg
Source Yeast
Species Mouse

Mouse Pdxp protein - orb383184 from Biorbyt

Category Protein
Species Mouse

Recombinant Mouse PDXP Protein (1-292 aa), His-tagged - PDXP-2491M from Creative Biomart

Category Protein
Source Yeast
Species Mouse
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