| Gene Symbol |
SQLE
|
| Entrez Gene |
6713
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
squalene epoxidase
|
| Other Description |
SE|squalene monooxygenase
|
| Swissprots |
Q14534 Q9UEK6
|
| Accessions |
EAW92079 Q14534 AF098865 AAD10823 AK055357 AK225085 AK295302 BAG58282 AK301792 BAG63246 AK313384 BAG36182 AM393564 CAL38441 BC017033 AAH17033 BG772453 BX647400 BX647605 CAI46076 D78129 BAA11209 D78130 BAA22372 DQ894657 ABM85583 XM_011517246 XP_011515548 NM_003129 NP_003120
|
| Function |
Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway.
|
| Subcellular Location |
Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
|
| Top Pathways |
Steroid biosynthesis
|
![Western Blot: SQLE Overexpression Lysate (Adult Normal) [NBP2-08034] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SQLE.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/14490_SQLE%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-08034-img0001.jpg)