Gene Symbol | SQLE |
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Entrez Gene | 6713 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | squalene epoxidase |
Other Description | SE|squalene monooxygenase |
Swissprots | Q14534 Q9UEK6 |
Accessions | EAW92079 Q14534 AF098865 AAD10823 AK055357 AK225085 AK295302 BAG58282 AK301792 BAG63246 AK313384 BAG36182 AM393564 CAL38441 BC017033 AAH17033 BG772453 BX647400 BX647605 CAI46076 D78129 BAA11209 D78130 BAA22372 DQ894657 ABM85583 XM_011517246 XP_011515548 NM_003129 NP_003120 |
Function | Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway. |
Subcellular Location | Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. |
Top Pathways | Steroid biosynthesis |
Squalene epoxidase CRISPR/Cas9 KO Plasmid (h) - sc-402870 from Santa Cruz Biotechnology
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Squalene epoxidase HDR Plasmid (h) - sc-402870-HDR from Santa Cruz Biotechnology
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Squalene epoxidase Double Nickase Plasmid (h) - sc-402870-NIC from Santa Cruz Biotechnology
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Squalene epoxidase Double Nickase Plasmid (h2) - sc-402870-NIC-2 from Santa Cruz Biotechnology
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Squalene epoxidase CRISPR Activation Plasmid (h) - sc-402870-ACT from Santa Cruz Biotechnology
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Squalene epoxidase CRISPR Activation Plasmid (h2) - sc-402870-ACT-2 from Santa Cruz Biotechnology
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Squalene epoxidase Lentiviral Activation Particles (h) - sc-402870-LAC from Santa Cruz Biotechnology
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Squalene epoxidase Lentiviral Activation Particles (h2) - sc-402870-LAC-2 from Santa Cruz Biotechnology
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Squalene epoxidase siRNA (h) - sc-61608 from Santa Cruz Biotechnology
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Squalene epoxidase shRNA Plasmid (h) - sc-61608-SH from Santa Cruz Biotechnology
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Squalene epoxidase shRNA (h) Lentiviral Particles - sc-61608-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU020681 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20550 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20550 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12073 from Sigma-Aldrich
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SQLE siRNA (Human) - CRH4582 from Cohesion Biosciences
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SQLE - MBS8209329 from MyBioSource
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shRNA set against Human SQLE (NM_003129.3) - SHH417588 from Creative biogene
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shRNA set against Human SQLE(NM_003129.3) - SHL031962 from Creative biogene
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SQLE shRNA Plasmid (Human) - CHH4582 from Cohesion Biosciences
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SQLE miRNA 3'UTR clone - MiUTR1H-09893 from Creative biogene
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