Gnas

Gene Symbol	Gnas
Entrez Gene	24896
Alt Symbol	Gnas1, Gnpas, Nesp55
Species	Rat
Gene Type	protein-coding
Description	GNAS complex locus
Other Description	G-alpha-8|GNAS|GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus|adenylate cyclase-stimulating G alpha protein|gnas {ECO:0000312|RGD:2716}|guanine nucleotide binding protein alpha s|guanine nucleotide-binding protein G-s, alpha subunit
Swissprots	Q792G6 P04894 Q05087 P08755 Q9Z1R8 Q45QM7 P63095
Accessions	AAD03032 AAD03033 EDL85091 P63095 Q63803 Q792G6 Q9Z213 AF105254 AAF63227 AF107844 AAD11801 AF107845 AAD11803 AF184151 AAF37806 BC061967 AAH61967 BC158589 AAI58590 BC168156 AAI68156 BF394587 CB770483 DQ120475 AAZ23814 DQ120476 AAZ23815 FQ212511 FQ214546 FQ219804 FQ226208 L10326 AAA41664 M12673 AAA41261 M17525 AAA40827 X84047 CAC39211 NM_019132 NP_062005 NM_001024823 NP_001019994 NM_001159653 NP_001153125 NM_001159656 NP_001153128 NM_021845 NP_068617
Function	Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Stimulates the Ras signaling pathway via RAPGEF2 (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250}. Secreted {ECO:0000250}. Note=Neuroendocrine secretory granules. {ECO:0000250}.
Tissue Specificity	Isoform Gnas-3 is abundant in brain with intermediate levels in skeletal muscle and very low levels in other tissues. {ECO:0000269|PubMed:8486667}.
Top Pathways	Oxytocin signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Inflammatory mediator regulation of TRP channels, Long-term depression

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Active rat GsaL full length protein - ab90723 from Abcam Category Protein Prices $410.00 Sizes 1 ml Source Baculovirus infected sf9 cells Species Rat

Active rat GsaL full length protein - ab90764 from Abcam Category Protein Prices $410.00 Sizes 1 ml Source Baculovirus infected sf9 cells Species Rat

Rat G protein alpha (mutated L227 + N295) full length protein - ab90406 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Rat

Rat G protein alpha (mutated Q212 L + D280 N) full length protein - ab90410 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Rat

Rat G protein alpha S (mutated D280 N) full length protein - ab90728 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Rat

Rat G protein alpha S full length protein - ab90407 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Rat

Rat GsaL (mutated Q227 L) full length protein - ab90771 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Rat

Rat GsaSLeu212 full length protein - ab90796 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Rat

Recombinant Rat GNAS Complex Locus - Gnas-1045R from Creative Biomart Category Protein Source Sf9 insect cells.

Recombinant Rat Neuroendocrine secretory protein 55(Gnas) - CSB-YP755279RA CSB-EP755279RA CSB-BP755279RA CSB-MP755279RA from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Rat

Recombinant Rat Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas(Gnas) ,partial - CSB-YP733974RA CSB-EP733974RA CSB-BP733974RA CSB-MP733974RA from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Rat

Recombinant Rat Guanine nucleotide-binding protein G(s) subunit alpha isoforms - CSB-YP351815RA CSB-EP351815RA CSB-BP351815RA CSB-MP351815RA from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Rat

Recombinant Rat GNAS/Gs alpha L - CSI13593 from Cell Science Prices $650.00 Sizes 1 ml Species Rat

Recombinant Rat GNAS/Gs alpha L Asn295 - CSI13594 from Cell Science Prices $650.00 Sizes 1 ml Species Rat

Recombinant Rat GNAS/Gs alpha L Leu227 - CSI13596 from Cell Science Prices $650.00 Sizes 1 ml Species Rat

Recombinant Rat GNAS/Gs alpha L Leu227/Asn295 - CSI13595 from Cell Science Prices $650.00 Sizes 1 ml Species Rat

Recombinant Rat GNAS/Gs alpha S - CSI13597 from Cell Science Prices $650.00 Sizes 1 ml Species Rat

Recombinant Rat GNAS/Gs alpha S Asn280 - CSI13599 from Cell Science Prices $650.00 Sizes 1 ml Species Rat

Recombinant Rat GNAS/Gs alpha S Leu212 - CSI13600 from Cell Science Prices $650.00 Sizes 1 ml Species Rat

Recombinant Rat GNAS/Gs alpha S Leu212/Asn280 - CSI13598 from Cell Science Prices $650.00 Sizes 1 ml Species Rat

Guanine nucleotide-binding protein G (s) subunit alpha isoforms short, Recombinant Protein - MBS1185037 from MyBioSource Category Protein Prices $305.00, $580.00, $1,165.00, $1,165.00, $1,395.00, $1,395.00, $1,850.00, $1,850.00, $2,310.00, $2,310.00, $2,310.00, $3,650.00 Sizes 50 µg (E-Coli), 200 µg (E-Coli), 50 µg (Baculovirus), 500 µg (E-Coli), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Rat

Guanine nucleotide-binding protein G (s) subunit alpha isoforms XLas (Gnas), partial, Recombinant Protein - MBS1482849 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Rat

Neuroendocrine secretory protein 55 (Gnas), Recombinant Protein - MBS1413517 from MyBioSource Category Protein Prices $960.00, $960.00, $1,185.00, $1,185.00, $1,440.00, $1,440.00, $1,905.00, $1,905.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Rat

Search more