| Gene Symbol |
TCTN3
|
| Entrez Gene |
26123
|
| Alt Symbol |
C10orf61, JBTS18, OFD4, TECT3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tectonic family member 3
|
| Other Description |
tectonic-3
|
| Swissprots |
Q8N7K1 A6NIC8 B4DR81 B0QZ90 Q96GF7 Q6P7P3 Q8NBQ0 Q6UW27 Q6ZQQ0 Q9Y3U1 Q6NUS6
|
| Accessions |
EAW49993 Q6NUS6 AI375376 AK075357 BAC11567 AK098295 BAC05278 AK128834 BAC87634 AK299141 BAG61193 AL050022 CAB43242 AW517317 AY359022 AAQ89381 BC009494 AAH09494 BC061582 AAH61582 BC068449 AAH68449 BI561516 BQ005427 BU188435 BU742551 CN427798 DQ278872 ABB90564 XM_005269690 XP_005269747 XM_011539627 XP_011537929 XM_011539628 XP_011537930 NM_001143973 NP_001137445 NM_015631 NP_056446
|
| Function |
Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). May be involved in apoptosis regulation. Necessary for signal transduction through the sonic hedgehog (Shh) signaling pathway. {ECO:0000250, ECO:0000269|PubMed:17464193, ECO:0000269|PubMed:22883145}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|