Gene Symbol | TCTN3 |
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Entrez Gene | 26123 |
Alt Symbol | C10orf61, JBTS18, OFD4, TECT3 |
Species | Human |
Gene Type | protein-coding |
Description | tectonic family member 3 |
Other Description | tectonic-3 |
Swissprots | Q8N7K1 A6NIC8 B4DR81 B0QZ90 Q96GF7 Q6P7P3 Q8NBQ0 Q6UW27 Q6ZQQ0 Q9Y3U1 Q6NUS6 |
Accessions | EAW49993 Q6NUS6 AI375376 AK075357 BAC11567 AK098295 BAC05278 AK128834 BAC87634 AK299141 BAG61193 AL050022 CAB43242 AW517317 AY359022 AAQ89381 BC009494 AAH09494 BC061582 AAH61582 BC068449 AAH68449 BI561516 BQ005427 BU188435 BU742551 CN427798 DQ278872 ABB90564 XM_005269690 XP_005269747 XM_011539627 XP_011537929 XM_011539628 XP_011537930 NM_001143973 NP_001137445 NM_015631 NP_056446 |
Function | Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). May be involved in apoptosis regulation. Necessary for signal transduction through the sonic hedgehog (Shh) signaling pathway. {ECO:0000250, ECO:0000269|PubMed:17464193, ECO:0000269|PubMed:22883145}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tect3 CRISPR/Cas9 KO Plasmid (h) - sc-411880 from Santa Cruz Biotechnology
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Tect3 HDR Plasmid (h) - sc-411880-HDR from Santa Cruz Biotechnology
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Tect3 Double Nickase Plasmid (h) - sc-411880-NIC from Santa Cruz Biotechnology
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Tect3 Double Nickase Plasmid (h2) - sc-411880-NIC-2 from Santa Cruz Biotechnology
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Tect3 CRISPR Activation Plasmid (h) - sc-411880-ACT from Santa Cruz Biotechnology
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Tect3 CRISPR Activation Plasmid (h2) - sc-411880-ACT-2 from Santa Cruz Biotechnology
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Tect3 Lentiviral Activation Particles (h) - sc-411880-LAC from Santa Cruz Biotechnology
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Tect3 Lentiviral Activation Particles (h2) - sc-411880-LAC-2 from Santa Cruz Biotechnology
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Tect3 siRNA (h) - sc-90630 from Santa Cruz Biotechnology
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Tect3 shRNA Plasmid (h) - sc-90630-SH from Santa Cruz Biotechnology
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Tect3 shRNA (h) Lentiviral Particles - sc-90630-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU075471 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21177 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21177 from Sigma-Aldrich
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TCTN3 siRNA (Human) - CRH8720 from Cohesion Biosciences
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TCTN3 - MBS8200036 from MyBioSource
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shRNA set against Human TCTN3 (NM_015631.5) - SHH425232 from Creative biogene
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Human TCTN3 siRNA - orb269222 from Biorbyt
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TCTN3 shRNA Plasmid (Human) - CHH8720 from Cohesion Biosciences
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TCTN3 miRNA 3'UTR clone - MiUTR3H-13050 from Creative biogene
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TCTN3 miRNA 3'UTR clone - MiUTR3H-13051 from Creative biogene
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