| Gene Symbol |
ADAMTS9
|
| Entrez Gene |
56999
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ADAM metallopeptidase with thrombospondin type 1 motif, 9
|
| Other Description |
A disintegrin and metalloproteinase with thrombospondin motifs 9|ADAM-TS 9|ADAM-TS9|ADAMTS-9|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9
|
| Swissprots |
A1L4L0 Q9P2N4 B7ZVX9 Q9NR29 B9ZVN0
|
| Accessions |
EAW65434 EAW65435 Q9P2N4 AB037733 BAA92550 AF261918 AAF89106 AF488803 AAO15765 AK124945 AK300357 BAG62098 AK303343 BAG64406 AK310571 BC026271 BC036770 BC130578 AAI30579 BC171764 AAI71764 BX482310 CD103111 XM_005265329 XP_005265386 XR_245151 NM_182920 NP_891550
|
| Function |
Cleaves the large aggregating proteoglycans, aggrecan and versican. Has a protease-independent function in promoting the transport from the endoplasmic reticulum to the Golgi apparatus of a variety of secretory cargos. {ECO:0000269|PubMed:12514189, ECO:0000269|PubMed:22419820}.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000250}. Endoplasmic reticulum {ECO:0000269|PubMed:22419820}.
|
| Tissue Specificity |
Highly expressed in all fetal tissues. Expressed in a number of adult tissues with highest expression in heart, placenta and skeletal muscle.
|