Gene Symbol | ADAMTS9 |
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Entrez Gene | 56999 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
Other Description | A disintegrin and metalloproteinase with thrombospondin motifs 9|ADAM-TS 9|ADAM-TS9|ADAMTS-9|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9 |
Swissprots | A1L4L0 Q9P2N4 B7ZVX9 Q9NR29 B9ZVN0 |
Accessions | EAW65434 EAW65435 Q9P2N4 AB037733 BAA92550 AF261918 AAF89106 AF488803 AAO15765 AK124945 AK300357 BAG62098 AK303343 BAG64406 AK310571 BC026271 BC036770 BC130578 AAI30579 BC171764 AAI71764 BX482310 CD103111 XM_005265329 XP_005265386 XR_245151 NM_182920 NP_891550 |
Function | Cleaves the large aggregating proteoglycans, aggrecan and versican. Has a protease-independent function in promoting the transport from the endoplasmic reticulum to the Golgi apparatus of a variety of secretory cargos. {ECO:0000269|PubMed:12514189, ECO:0000269|PubMed:22419820}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. Endoplasmic reticulum {ECO:0000269|PubMed:22419820}. |
Tissue Specificity | Highly expressed in all fetal tissues. Expressed in a number of adult tissues with highest expression in heart, placenta and skeletal muscle. |
ADAMTS-9 CRISPR/Cas9 KO Plasmid (h) - sc-402605 from Santa Cruz Biotechnology
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ADAMTS-9 HDR Plasmid (h) - sc-402605-HDR from Santa Cruz Biotechnology
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ADAMTS-9 Double Nickase Plasmid (h) - sc-402605-NIC from Santa Cruz Biotechnology
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ADAMTS-9 Double Nickase Plasmid (h2) - sc-402605-NIC-2 from Santa Cruz Biotechnology
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ADAMTS-9 CRISPR Activation Plasmid (h) - sc-402605-ACT from Santa Cruz Biotechnology
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ADAMTS-9 CRISPR Activation Plasmid (h2) - sc-402605-ACT-2 from Santa Cruz Biotechnology
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ADAMTS-9 Lentiviral Activation Particles (h) - sc-402605-LAC from Santa Cruz Biotechnology
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ADAMTS-9 Lentiviral Activation Particles (h2) - sc-402605-LAC-2 from Santa Cruz Biotechnology
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ADAMTS-9 siRNA (h) - sc-45817 from Santa Cruz Biotechnology
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ADAMTS-9 shRNA Plasmid (h) - sc-45817-SH from Santa Cruz Biotechnology
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ADAMTS-9 shRNA (h) Lentiviral Particles - sc-45817-V from Santa Cruz Biotechnology
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ADAMTS9 RNAi - H00056999-R01 from Novus Biologicals
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MISSION® esiRNA - EHU036531 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2839 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2839 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09274 from Sigma-Aldrich
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ADAMTS9 siRNA (Human) - CRJ1282 from Cohesion Biosciences
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ADAMTS9 - MBS8236129 from MyBioSource
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shRNA set against Human ADAMTS9 (NM_182920.1) - SHH231934 from Creative biogene
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ADAMTS9 shRNA Plasmid (Human) - CHJ1282 from Cohesion Biosciences
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ADAMTS9 miRNA 3'UTR clone - MiUTR1H-00178 from Creative biogene
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