| Gene Symbol |
TAS2R40
|
| Entrez Gene |
259286
|
| Alt Symbol |
GPR60, T2R40, T2R58
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
taste receptor, type 2, member 40
|
| Other Description |
G protein-coupled receptor 60|G-protein coupled receptor 60|taste receptor type 2 member 40|taste receptor type 2 member 58
|
| Swissprots |
P59535 A4D2I2 Q645W6
|
| Accessions |
AAM19320 BAD98041 BAD98042 BAD98043 CAI53578 EAL23782 EAW51882 P59535 BC101795 AAI01796 BC101797 AAI01798 NM_176882 NP_795363
|
| Function |
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
|
| Top Pathways |
Taste transduction
|
![Western Blot: TAS2R40 Overexpression Lysate (Adult Normal) [NBL1-16709] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TAS2R40.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/8178_TAS2R40%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-16709-img0002.jpg)