Gene Symbol | TAS2R40 |
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Entrez Gene | 259286 |
Alt Symbol | GPR60, T2R40, T2R58 |
Species | Human |
Gene Type | protein-coding |
Description | taste receptor, type 2, member 40 |
Other Description | G protein-coupled receptor 60|G-protein coupled receptor 60|taste receptor type 2 member 40|taste receptor type 2 member 58 |
Swissprots | P59535 A4D2I2 Q645W6 |
Accessions | AAM19320 BAD98041 BAD98042 BAD98043 CAI53578 EAL23782 EAW51882 P59535 BC101795 AAI01796 BC101797 AAI01798 NM_176882 NP_795363 |
Function | Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. |
Top Pathways | Taste transduction |
T2R40 CRISPR/Cas9 KO Plasmid (h) - sc-415266 from Santa Cruz Biotechnology
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T2R40 HDR Plasmid (h) - sc-415266-HDR from Santa Cruz Biotechnology
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T2R40 Double Nickase Plasmid (h) - sc-415266-NIC from Santa Cruz Biotechnology
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T2R40 Double Nickase Plasmid (h2) - sc-415266-NIC-2 from Santa Cruz Biotechnology
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T2R40 CRISPR Activation Plasmid (h) - sc-415266-ACT from Santa Cruz Biotechnology
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T2R40 CRISPR Activation Plasmid (h2) - sc-415266-ACT-2 from Santa Cruz Biotechnology
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T2R40 Lentiviral Activation Particles (h) - sc-415266-LAC from Santa Cruz Biotechnology
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T2R40 Lentiviral Activation Particles (h2) - sc-415266-LAC-2 from Santa Cruz Biotechnology
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T2R40 siRNA (h) - sc-89669 from Santa Cruz Biotechnology
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T2R40 shRNA Plasmid (h) - sc-89669-SH from Santa Cruz Biotechnology
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T2R40 shRNA (h) Lentiviral Particles - sc-89669-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN21025 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21025 from Sigma-Aldrich
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TAS2R40 siRNA (Human) - CRJ6810 from Cohesion Biosciences
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TAS2R40 RNAi - H00259286-R02 from Novus Biologicals
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TAS2R40 - MBS8202796 from MyBioSource
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shRNA set against Human TAS2R40 (NM_176882.1) - SHH423552 from Creative biogene
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TAS2R40 shRNA Plasmid (Human) - CHJ6810 from Cohesion Biosciences
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TAS2R40 miRNA 3'UTR clone - MiUTR1H-10198 from Creative biogene
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