CD40

Gene Symbol CD40
Entrez Gene 958
Alt Symbol Bp50, CDW40, TNFRSF5, p50
Species Human
Gene Type protein-coding
Description CD40 molecule, TNF receptor superfamily member 5
Other Description B cell surface antigen CD40|B cell-associated molecule|CD40 antigen (TNF receptor superfamily member 5)|CD40 type II isoform|CD40L receptor|nerve growth factor receptor-related B-lymphocyte activation molecule|tumor necrosis factor receptor superfamily member 5
Swissprots Q5U007 E1P5S9 Q9BYU0 Q7M4Q8 Q5JY15 Q53GN5 P25942 Q86YK5
Accessions AAR84238 ABI49511 ABK41937 CAJ00027 CAJ00028 CAJ00033 CAJ00034 CAJ00124 CAJ00125 CAJ00728 CAJ00729 CAL31951 CAL31952 CAL47757 CAL47758 CAL47760 CAL47761 CAL99221 CAL99222 CAL99226 CAL99227 CAQ64629 CAQ64630 CAX20923 CAX20924 CAZ64457 CAZ64458 CBJ55369 CBJ55370 CBL93995 CBX32768 CBX32769 CBX55113 CBX55114 CBX55116 CBX55117 CBX89251 CBX89252 CBY65289 CBY65290 CCA63957 CCA63958 CDH93531 CDH93532 EAW75757 EAW75758 EAW75759 EAW75760 EAW75761 EAW75762 EAW75763 P25942 AB209660 BAD92897 AJ300189 CAC29424 AK222896 BAD96616 AY225405 AAO43990 BC012419 AAH12419 BC064518 AAH64518 BM761221 BT019901 AAV38704 BX364284 BX364285 DQ891804 ABM82730 DQ894988 ABM85914 HY063089 HY088000 XM_005260617 XP_005260674 XM_005260619 XP_005260676 XM_011529109 XP_011527411 XR_936660 NM_001250 NP_001241 NM_001302753 NP_001289682 NM_152854 NP_690593 NR_126502
Function Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Subcellular Location Isoform I: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity B-cells and in primary carcinomas.
Top Pathways Toll-like receptor signaling pathway, Epstein-Barr virus infection, Cell adhesion molecules (CAMs), Asthma, HTLV-I infection

CD40 (BE-1) - sc-65263 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD40 (BE-1): sc-65263. Western blot analysis of CD40 expression in BJAB whole cell lysate under non-reducing conditions.

CD40 (C-20) - sc-975 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CD40 (C-20): sc-975. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human lymphoma showing membrane staining.

CD40 (EA-5) - sc-65264 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD40 (EA-5): sc-65264. Western blot analysis of CD40 expression in L-428 whole cell lysate.

CD40 (H-10) - sc-13128 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD40 (H-10): sc-13128. Immunoperoxidase staining of formalin fixed, paraffin-embedded human spleen tissue showing cytoplasmic staining of cells in white pulp and cells in red pulp.

CD40 (G-14) - sc-30683 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CD40 (H-15) - sc-30685 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CD40 (H-120) - sc-9096 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CD40 (H-120): sc-9096. Immunofluorescence staining of methanol-fixed A-431 cells showing membrane localization.

CD40 (LOB-11) - sc-13528 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD40 (LOB-11): sc-13528. Western blot analysis of CD40 expression in BJAB whole cell lysate.

CD40 (MAB89) - sc-59047 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

CD40 (N-16) - sc-974 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CD40 (N-16): sc-974. Western blot analysis of CD40 expression in NAMALWA whole cell lysate.

CD40 (S-17) - sc-30681 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CD40 (S-17): sc-30681. Western blot analysis of CD40 expression in non-transfected 293: sc-110760 (A), human CD40 transfected 293: sc-112948 (B) and BJAB (C) whole cell lysates.

CD40 (T-20) - sc-1731 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CD40 (T-20): sc-1731. Western blot analysis of CD40 expression in BJAB whole cell lysate.

Anti-CD40 (phospho T254) antibody - ab79278 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD40 (phospho T254) antibody (ab79278) at 1/500 dilutionLane 1 : COLO cell extract, treated with Insulin (0.01U/ml, 15mins)Lane 2 : COLO cell extract, treated with Insulin (0.01U/ml, 15mins) with immunising phosphopeptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-CD40 antibody - ab58391 from Abcam

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD40 antibody (ab58391) at 1/500 dilutionLane 1 : COS7 cell extract with no immunizing peptideLane 2 : COS7 cell extract with immunizing peptide

Anti-CD40 antibody - ab65853 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CD40 antibody (ab65853) at 2 µg/ml + Hela cell lysate

Anti-CD40 antibody - ab113701 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD40 antibody (ab113701) at 1 µg/mlLane 1 : Spleen (Human) Tissue Lysate - adult normal tissue (ab29699)Lane 2 : Thymus (Human) Tissue Lysate - adult normal tissue (ab30146)Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-CD40 antibody - ab58612 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab58612, at 1/100 dilution, staining CD40 in formalin fixed Human tonsil tissue by Immunohistochemistry.

Anti-CD40 antibody - ab87233 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CD40 antibody (ab87233) at 1 µg/ml + human fetal thymus lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-CD40 antibody - ab10959 from Abcam

Prices $416.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-CD40 antibody [11E9] - ab50849 from Abcam

Prices $372.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 11E9

Anti-CD40 antibody [3/23] - ab22469 from Abcam

Prices $379.00
Sizes 125 µg
Host Rat
Clonality Monoclonal
Clone 3/23
ab22469 staining CD40 in Mouse Spleen cells by flow cytometric analysis.

Anti-CD40 antibody [4G3] - ab135293 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4G3
Anti-CD40 antibody [4G3] (ab135293) at 5 µg/ml + Recombinant Protein at 0.2 µg

Anti-CD40 antibody [5C3] - ab134379 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5C3

Anti-CD40 antibody [5C3] - ab176456 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5C3

Anti-CD40 antibody [5C3] (Allophycocyanin) - ab134382 from Abcam

Prices $188.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 5C3
Flow cytometry analysis of normal Human peripheral blood cells with Mouse IgG1 K Isotype Control APC (open histogram) or ab134382 at 5 µl (0.06 µg)/test (filled histogram). Cells in the lymphocyte gate were used for analysis.
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