CD40

Gene Symbol CD40
Entrez Gene 958
Alt Symbol Bp50, CDW40, TNFRSF5, p50
Species Human
Gene Type protein-coding
Description CD40 molecule, TNF receptor superfamily member 5
Other Description B cell surface antigen CD40|B cell-associated molecule|CD40 antigen (TNF receptor superfamily member 5)|CD40 type II isoform|CD40L receptor|nerve growth factor receptor-related B-lymphocyte activation molecule|tumor necrosis factor receptor superfamily member 5
Swissprots Q5U007 E1P5S9 Q9BYU0 Q7M4Q8 Q5JY15 Q53GN5 P25942 Q86YK5
Accessions AAR84238 ABI49511 ABK41937 CAJ00027 CAJ00028 CAJ00033 CAJ00034 CAJ00124 CAJ00125 CAJ00728 CAJ00729 CAL31951 CAL31952 CAL47757 CAL47758 CAL47760 CAL47761 CAL99221 CAL99222 CAL99226 CAL99227 CAQ64629 CAQ64630 CAX20923 CAX20924 CAZ64457 CAZ64458 CBJ55369 CBJ55370 CBL93995 CBX32768 CBX32769 CBX55113 CBX55114 CBX55116 CBX55117 CBX89251 CBX89252 CBY65289 CBY65290 CCA63957 CCA63958 CDH93531 CDH93532 EAW75757 EAW75758 EAW75759 EAW75760 EAW75761 EAW75762 EAW75763 P25942 AB209660 BAD92897 AJ300189 CAC29424 AK222896 BAD96616 AY225405 AAO43990 BC012419 AAH12419 BC064518 AAH64518 BM761221 BT019901 AAV38704 BX364284 BX364285 DQ891804 ABM82730 DQ894988 ABM85914 HY063089 HY088000 XM_005260617 XP_005260674 XM_005260619 XP_005260676 XM_011529109 XP_011527411 XR_936660 NM_001250 NP_001241 NM_001302753 NP_001289682 NM_152854 NP_690593 NR_126502
Function Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Subcellular Location Isoform I: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity B-cells and in primary carcinomas.
Top Pathways Toll-like receptor signaling pathway, Epstein-Barr virus infection, Cell adhesion molecules (CAMs), Asthma, HTLV-I infection

CD40 CRISPR/Cas9 KO Plasmid (h) - sc-400524 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD40 HDR Plasmid (h) - sc-400524-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD40 Double Nickase Plasmid (h) - sc-400524-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD40 Double Nickase Plasmid (h2) - sc-400524-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD40 CRISPR Activation Plasmid (h) - sc-400524-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD40 CRISPR Activation Plasmid (h2) - sc-400524-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD40 Lentiviral Activation Particles (h) - sc-400524-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD40 Lentiviral Activation Particles (h2) - sc-400524-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD40 siRNA (h) - sc-29250 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD40 shRNA Plasmid (h) - sc-29250-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD40 shRNA (h) Lentiviral Particles - sc-29250-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD40/TNFRSF5 RNAi - H00000958-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CD40/TNFRSF5 RNAi - H00000958-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU066671 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1113 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1113 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06659 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06659

CD40 siRNA (Human) - CRH0680 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CD40 - MBS8213026 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CD40 (NM_001250.4) - SHH259105 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CD40(NM_152854.2) - SHG157465 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CD40(NM_001250.4) - SHG157525 from Creative biogene

Category siRNA
Species Reactivities Human

Human CD40 siRNA - orb261182 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CD40 shRNA Plasmid (Human) - CHH0680 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CD40 miRNA 3'UTR clone - MiUTR1H-01878 from Creative biogene

Species Reactivities Human
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