| Gene Symbol |
TAX1BP1
|
| Entrez Gene |
8887
|
| Alt Symbol |
CALCOCO3, T6BP, TXBP151
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Tax1 (human T-cell leukemia virus type I) binding protein 1
|
| Other Description |
TRAF6-binding protein|tax1-binding protein 1
|
| Swissprots |
Q9UI88 Q86VP1 Q13311 O60398 O95770 Q9BQG5 B4DKU7 A4D196 E7ENV2
|
| Accessions |
AAC13359 AAD15412 CCQ43345 EAL24213 EAW93901 EAW93902 EAW93903 EAW93904 Q86VP1 AA481381 AF090891 AAF24016 AF268075 AAG03025 AK000098 AK296720 BAG59309 AK299729 BAG61627 AK301064 BAG62671 AK309757 AK314292 BAG36949 AL136586 CAB66521 AM393835 CAL38710 BC024600 BC050358 AAH50358 BP280714 BU679319 CR457056 CAG33337 CR533556 CAG38587 DB455556 DB553566 DC424592 U33821 AAA75595 XM_005249900 XP_005249957 NM_001079864 NP_001073333 NM_001206901 NP_001193830 NM_001206902 NP_001193831 NM_006024 NP_006015
|
| Function |
Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. {ECO:0000269|PubMed:10435631, ECO:0000269|PubMed:10920205}.
|
| Tissue Specificity |
Expressed in all tissues tested.
|