Gene Symbol | TAX1BP1 |
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Entrez Gene | 8887 |
Alt Symbol | CALCOCO3, T6BP, TXBP151 |
Species | Human |
Gene Type | protein-coding |
Description | Tax1 (human T-cell leukemia virus type I) binding protein 1 |
Other Description | TRAF6-binding protein|tax1-binding protein 1 |
Swissprots | Q9UI88 Q86VP1 Q13311 O60398 O95770 Q9BQG5 B4DKU7 A4D196 E7ENV2 |
Accessions | AAC13359 AAD15412 CCQ43345 EAL24213 EAW93901 EAW93902 EAW93903 EAW93904 Q86VP1 AA481381 AF090891 AAF24016 AF268075 AAG03025 AK000098 AK296720 BAG59309 AK299729 BAG61627 AK301064 BAG62671 AK309757 AK314292 BAG36949 AL136586 CAB66521 AM393835 CAL38710 BC024600 BC050358 AAH50358 BP280714 BU679319 CR457056 CAG33337 CR533556 CAG38587 DB455556 DB553566 DC424592 U33821 AAA75595 XM_005249900 XP_005249957 NM_001079864 NP_001073333 NM_001206901 NP_001193830 NM_001206902 NP_001193831 NM_006024 NP_006015 |
Function | Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. {ECO:0000269|PubMed:10435631, ECO:0000269|PubMed:10920205}. |
Tissue Specificity | Expressed in all tissues tested. |
T6BP CRISPR/Cas9 KO Plasmid (h) - sc-404858 from Santa Cruz Biotechnology
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T6BP HDR Plasmid (h) - sc-404858-HDR from Santa Cruz Biotechnology
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T6BP Double Nickase Plasmid (h) - sc-404858-NIC from Santa Cruz Biotechnology
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T6BP Double Nickase Plasmid (h2) - sc-404858-NIC-2 from Santa Cruz Biotechnology
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T6BP CRISPR Activation Plasmid (h) - sc-404858-ACT from Santa Cruz Biotechnology
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T6BP CRISPR Activation Plasmid (h2) - sc-404858-ACT-2 from Santa Cruz Biotechnology
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T6BP Lentiviral Activation Particles (h) - sc-404858-LAC from Santa Cruz Biotechnology
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T6BP Lentiviral Activation Particles (h2) - sc-404858-LAC-2 from Santa Cruz Biotechnology
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T6BP siRNA (h) - sc-106831 from Santa Cruz Biotechnology
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T6BP shRNA Plasmid (h) - sc-106831-SH from Santa Cruz Biotechnology
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T6BP shRNA (h) Lentiviral Particles - sc-106831-V from Santa Cruz Biotechnology
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TAX1BP1 RNAi - H00008887-R01 from Novus Biologicals
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MISSION® esiRNA - EHU041771 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21042 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21042 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08245 from Sigma-Aldrich
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TAX1BP1 siRNA (Human) - CRH5873 from Cohesion Biosciences
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TAX1BP1 - MBS8230227 from MyBioSource
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shRNA set against Human TAX1BP1 (NM_006024.6) - SHH423660 from Creative biogene
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Human TAX1BP1 siRNA - orb266375 from Biorbyt
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TAX1BP1 shRNA Plasmid (Human) - CHH5873 from Cohesion Biosciences
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TAX1BP1 miRNA 3'UTR clone - MiUTR3H-07574 from Creative biogene
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TAX1BP1 miRNA 3'UTR clone - MiUTR3H-07575 from Creative biogene
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