| Gene Symbol |
PIANP
|
| Entrez Gene |
196500
|
| Alt Symbol |
C12orf53, LEDA1, PANP, leda-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
PILR alpha associated neural protein
|
| Other Description |
PILR alpha-associated neural protein|PILR-associating neural protein|liver endothelial differentiation-associated protein-1|paired immunoglobin-like type 2 receptor-associating neural protein
|
| Swissprots |
B3KPF7 B3KRI6 A8K0T3 Q6UX35 Q8IYJ0
|
| Accessions |
EAW88750 EAW88751 EAW88752 EAW88753 EAW88754 Q8IYJ0 AA653479 AK056295 BAG51669 AK091596 BAG52388 AK091656 BAG52398 AK095854 BAG53145 AK289648 BAF82337 AL831874 AY358534 AAQ88898 BC035736 AAH35736 BM703122 DA090039 DB496995 XM_006718970 XP_006719033 XM_011520926 XP_011519228 NM_001244014 NP_001230943 NM_001244015 NP_001230944 NM_153685 NP_710152
|
| Function |
Acts as a ligand for PILRA in neural tissues, where it may be involved in immune regulation. {ECO:0000269|PubMed:21241660}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Mainly expressed in adult brain and cerebellum. Weaker expression in fetal brain and virtually no expression in spleen, heart, kidney, liver and dorsal ganglion relative to brain. {ECO:0000269|PubMed:21241660}.
|
![Western Blot: PILR alpha associated neural protein Overexpression Lysate (Native) [NBP2-05244] - PILR alpha associated neural protein Overexpression Lysate (Native) Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for C12orf53.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5937_PILR-alpha-associated-neural-protein-Overexpression-Lysate-(Native)-Western-Blot-NBP2-05244-img0002.jpg)