Gene Symbol | PIANP |
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Entrez Gene | 196500 |
Alt Symbol | C12orf53, LEDA1, PANP, leda-1 |
Species | Human |
Gene Type | protein-coding |
Description | PILR alpha associated neural protein |
Other Description | PILR alpha-associated neural protein|PILR-associating neural protein|liver endothelial differentiation-associated protein-1|paired immunoglobin-like type 2 receptor-associating neural protein |
Swissprots | B3KPF7 B3KRI6 A8K0T3 Q6UX35 Q8IYJ0 |
Accessions | EAW88750 EAW88751 EAW88752 EAW88753 EAW88754 Q8IYJ0 AA653479 AK056295 BAG51669 AK091596 BAG52388 AK091656 BAG52398 AK095854 BAG53145 AK289648 BAF82337 AL831874 AY358534 AAQ88898 BC035736 AAH35736 BM703122 DA090039 DB496995 XM_006718970 XP_006719033 XM_011520926 XP_011519228 NM_001244014 NP_001230943 NM_001244015 NP_001230944 NM_153685 NP_710152 |
Function | Acts as a ligand for PILRA in neural tissues, where it may be involved in immune regulation. {ECO:0000269|PubMed:21241660}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Mainly expressed in adult brain and cerebellum. Weaker expression in fetal brain and virtually no expression in spleen, heart, kidney, liver and dorsal ganglion relative to brain. {ECO:0000269|PubMed:21241660}. |
C12orf53 CRISPR/Cas9 KO Plasmid (h) - sc-414964 from Santa Cruz Biotechnology
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C12orf53 HDR Plasmid (h) - sc-414964-HDR from Santa Cruz Biotechnology
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C12orf53 Double Nickase Plasmid (h) - sc-414964-NIC from Santa Cruz Biotechnology
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C12orf53 Double Nickase Plasmid (h2) - sc-414964-NIC-2 from Santa Cruz Biotechnology
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C12orf53 CRISPR Activation Plasmid (h) - sc-414964-ACT from Santa Cruz Biotechnology
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C12orf53 CRISPR Activation Plasmid (h2) - sc-414964-ACT-2 from Santa Cruz Biotechnology
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C12orf53 Lentiviral Activation Particles (h) - sc-414964-LAC from Santa Cruz Biotechnology
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C12orf53 Lentiviral Activation Particles (h2) - sc-414964-LAC-2 from Santa Cruz Biotechnology
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C12orf53 siRNA (h) - sc-96043 from Santa Cruz Biotechnology
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C12orf53 shRNA Plasmid (h) - sc-96043-SH from Santa Cruz Biotechnology
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C12orf53 shRNA (h) Lentiviral Particles - sc-96043-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU154201 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4264 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4264 from Sigma-Aldrich
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PIANP siRNA (Human) - CRJ6180 from Cohesion Biosciences
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Human PIANP siRNA - orb276681 from Biorbyt
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PIANP shRNA Plasmid (Human) - CHJ6180 from Cohesion Biosciences
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