SELPLG

Gene Symbol SELPLG
Entrez Gene 6404
Alt Symbol CD162, CLA, PSGL-1, PSGL1
Species Human
Gene Type protein-coding
Description selectin P ligand
Other Description P-selectin glycoprotein ligand 1|cutaneous lymphocyte-associated associated antigen
Swissprots Q14242 J3KMX6 B7Z5C7 B4DQC3 Q6GTW7 Q8N7J7 A8K2Y0 Q12775
Accessions AAA74577 AAP81163 CAG14915 CAG14916 EAW97824 EAW97825 Q14242 AK098315 BAC05283 AK127638 BAC87066 AK225644 AK290395 BAF83084 AK295238 BAG58231 AK298738 BAG60885 AK298742 BAH12863 AK300057 BAG61866 BC029782 AAH29782 CA427270 DC339004 DQ892117 ABM83043 DQ895313 ABM86239 U02297 AAC50061 XM_005269076 XP_005269133 NM_001206609 NP_001193538 NM_003006 NP_002997
Function A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture. {ECO:0000269|PubMed:11566773, ECO:0000269|PubMed:12403782}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed on neutrophils, monocytes and most lymphocytes.
Top Pathways Cell adhesion molecules (CAMs), Staphylococcus aureus infection

PSGL-1 (C-9) - sc-398402 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PSGL-1 (C-9): sc-398402. Western blot analysis of PSGL-1 expression in non-transfected 293T: sc-117752 (A), human PSGL-1 transfected 293T: sc-114271 (B), AML-193 (C) and CCRF-CEM (D) whole cell lysates.

PSGL-1 (G-9) - sc-365506 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PSGL-1 (G-9): sc-365506. Western blot analysis of PSGL-1 expression in non-transfected: sc-117752 (A) and human PSGL-1 transfected: sc-114271 (B) 293T whole cell lysates.

PSGL-1 (H-1) - sc-365423 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PSGL-1 (H-1): sc-365423. Western blot analysis of PSGL-1 expression in non-transfected: sc-117752 (A) and human PSGL-1 transfected: sc-114271 (B) 293T whole cell lysates.

PSGL-1 (215) - sc-32302 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PSGL-1 PE: sc-32302 PE. Extracellular FCM analysis of H.PBL cells. Solid black line histogram represents control mouse IgG.

PSGL-1 (PL1/3E2-25-5) - sc-80537 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PSGL-1 (PL1/3E2-25-5): sc-80537. Western blot analysis of PSGL-1 expression in AML-193 whole cell lysate.

PSGL-1 (C-19) - sc-10172 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PSGL-1 (C-19): sc-10172. Western blot analysis of PSGL-1 expression in non-transfected: sc-117752 (A) and human PSGL-1 transfected: sc-114271 (B) 293T whole cell lysates.

PSGL-1 (PL1) - sc-18855 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PSGL-1 (PL1) PE: sc-18855 PE. FCM analysis of human peripheral blood leukocytes. Quadrant markers were set based on the isotype control, normal mouse IgG<sub>1</sub>: sc-2866.

PSGL-1 (PL2) - sc-18856 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PSGL-1 (PL2) FITC: sc-18856 FITC. FCM analysis of human platelets. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-2855.

PSGL-1 (KPL1) - sc-13535 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PSGL-1 (KPL1) FITC: sc-13535 FITC. FCM analysis of human peripheral blood leukocytes. Quadrant markers were set based on the isotype control, normal mouse IgG<sub>1</sub>: sc-2855.

PSGL-1 (N-16) - sc-10169 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PSGL-1 (N-16): sc-10169. Western blot analysis of PSGL-1 expression in non-transfected: sc-117752 (A) and human PSGL-1 transfected: sc-114271 (B) 293T whole cell lysates.

PSGL-1 (H-300) - sc-20929 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PSGL-1 (H-300): sc-20929. Western blot analysis of PSGL-1 expression in non-transfected: sc-110760 (A) and human PSGL-1 transfected: sc-159212 (B) 293 whole cell lysates.

PSGL-1 (3H1915) - sc-71940 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PSGL-1 (3H1915): sc-71940. Western blot analysis of PSGL-1 expression in CCRF-CEM whole cell lysate.

Anti-CD162 antibody - ab66882 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
CD162 was immunoprecipitated using 0.5mg Rat thymus tissue extract, 5µg of Rabbit polyclonal to CD162 and 50µl of protein G magnetic beads (+). No antibody was added to the control (-).The antibody was incubated under agitation with Protein G beads for 10min, Rat thymus tissue extract lysate diluted in RIPA buffer was added to each sample and incubated for a further 10min under agitation.Proteins were eluted by addition of 40µl SDS loading buffer and incubated for 10min at 70°C; 10µl of each sample was separated on a SDS PAGE gel, transferred to a nitrocellulose membrane, blocked with 5% BSA and probed with ab66882.Secondary: Mouse monoclonal [SB62a] Secondary Antibody to Rabbit IgG light chain (HRP) (ab99697).Band: 105kDa; CD162

Anti-CD162 antibody - ab196779 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of HeLa cells labeling CD162 with ab196779 at 1/50 dilution.

Anti-CD162 antibody - ab134243 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CD162 antibody (ab134243) at 1 µg/ml + Human fetal heart lysate at 10 µg

Anti-CD162 antibody [5D881210PL2] - ab189102 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 5D881210PL2
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human colon, plasma cells tissue labelling CD162 with ab189102 at 10 µg/ml.

Anti-CD162 antibody [EPR1967Y] - ab68143 from Abcam

Prices $381.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR1967Y
ab681432(Red) staining CD162 in Human bronchial tissue sections by Immunohistochemistry (Glycolmethacrylate sections). Tissue was embedded in Glycolmethacrylate and floated onto 0.2% ammonia solution prior to adherence to slides.Samples were incubated with primary antibody (1/200) for 1 hour. Samples were also stained with a neutrophil elastase antibody( Brown). Sections were counterstained with haematoxylin.Key: E + x200 magnification and F = x500 magnification. * = Double stained cells. 

Anti-CD162 antibody [HECA-452] - ab110096 from Abcam

Prices $376.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone HECA-452
ab110096 at 10µg/ml staining CD162 in Formalin/PFA-fixed paraffin-embedded Human spleen tissue.

Anti-CD162 antibody [KPL-1] - ab78188 from Abcam

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone KPL-1
Human peripheral blood lymphocytes stained with ab78188 (red line). Human whole blood was processed using a modified protocol based on Chow et al, 2005 (PMID: 16080188). In brief, human whole blood was fixed in 4% formaldehyde (methanol-free) for 10 min at 22°C. Red blood cells were then lyzed by the addition of Triton X-100 (final concentration - 0.1%) for 15 min at 37°C. For experimentation, cells were treated with 50% methanol (-20°C) for 15 min at 4°C. Cells were then incubated with the antibody (ab78188, 0.01μg/1x106 cells) for 30 min at 4°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 4°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >30,000 total events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. Gating strategy - periphe

Anti-CD162 antibody [TB5] - ab3986 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone TB5

Anti-CD162 antibody [TC2] - ab112069 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone TC2

Anti-CD162 antibody [TC2] (Allophycocyanin) - ab112465 from Abcam

Prices $370.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone TC2

Anti-CD162 antibody [TC2] (FITC) - ab88033 from Abcam

Prices $188.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone TC2
ah88033 detecting CD162 in Human peripheral blood cells by Flow cytometry

Anti-CD162 antibody [TC2] (Phycoerythrin) - ab105064 from Abcam

Prices $370.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone TC2

Anti-SELPLG / PSGL-1 / CD162 Antibody - LS-C14361 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
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