| Gene Symbol |
KIF24
|
| Entrez Gene |
347240
|
| Alt Symbol |
C9orf48, bA571F15.4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
kinesin family member 24
|
| Other Description |
kinesin-like protein KIF24
|
| Swissprots |
Q5T7B7 Q6ZUZ2 Q2TB93 Q86XZ0 Q6ZU97 Q5T7B8 Q5T7B5 Q9NV43
|
| Accessions |
EAW58466 Q5T7B8 AK001795 AK125180 BAC86074 AK125872 BAC86329 AK310014 BC048311 AAH48311 BC110502 AAI10503 BC110503 AAI10504 BE856625 BF895212 BP871643 BU660279 DA906271 DT932659 DV080193 DV080194 XM_005251450 XP_005251507 XM_005251451 XP_005251508 XM_006716764 XP_006716827 XM_011517860 XP_011516162 XM_011517861 XP_011516163 XM_011517862 XP_011516164 XM_011517863 XP_011516165 NM_194313 NP_919289
|
| Function |
Microtubule-dependent motor protein that acts as a negative regulator of ciliogenesis by mediating recruitment of CCP110 to mother centriole in cycling cells, leading to restrict nucleation of cilia at centrioles. Mediates depolymerization of microtubules of centriolar origin, possibly to suppress aberrant cilia formation. {ECO:0000269|PubMed:21620453}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:21620453}. Note=Primarily localizes to the mother centriole/basal body and is either absent at daughter centriole.
|