Gene Symbol | KIF24 |
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Entrez Gene | 347240 |
Alt Symbol | C9orf48, bA571F15.4 |
Species | Human |
Gene Type | protein-coding |
Description | kinesin family member 24 |
Other Description | kinesin-like protein KIF24 |
Swissprots | Q5T7B7 Q6ZUZ2 Q2TB93 Q86XZ0 Q6ZU97 Q5T7B8 Q5T7B5 Q9NV43 |
Accessions | EAW58466 Q5T7B8 AK001795 AK125180 BAC86074 AK125872 BAC86329 AK310014 BC048311 AAH48311 BC110502 AAI10503 BC110503 AAI10504 BE856625 BF895212 BP871643 BU660279 DA906271 DT932659 DV080193 DV080194 XM_005251450 XP_005251507 XM_005251451 XP_005251508 XM_006716764 XP_006716827 XM_011517860 XP_011516162 XM_011517861 XP_011516163 XM_011517862 XP_011516164 XM_011517863 XP_011516165 NM_194313 NP_919289 |
Function | Microtubule-dependent motor protein that acts as a negative regulator of ciliogenesis by mediating recruitment of CCP110 to mother centriole in cycling cells, leading to restrict nucleation of cilia at centrioles. Mediates depolymerization of microtubules of centriolar origin, possibly to suppress aberrant cilia formation. {ECO:0000269|PubMed:21620453}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:21620453}. Note=Primarily localizes to the mother centriole/basal body and is either absent at daughter centriole. |
KIF24 CRISPR/Cas9 KO Plasmid (h) - sc-415625 from Santa Cruz Biotechnology
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KIF24 HDR Plasmid (h) - sc-415625-HDR from Santa Cruz Biotechnology
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KIF24 Double Nickase Plasmid (h) - sc-415625-NIC from Santa Cruz Biotechnology
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KIF24 Double Nickase Plasmid (h2) - sc-415625-NIC-2 from Santa Cruz Biotechnology
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KIF24 CRISPR Activation Plasmid (h) - sc-415625-ACT from Santa Cruz Biotechnology
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KIF24 CRISPR Activation Plasmid (h2) - sc-415625-ACT-2 from Santa Cruz Biotechnology
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KIF24 Lentiviral Activation Particles (h) - sc-415625-LAC from Santa Cruz Biotechnology
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KIF24 Lentiviral Activation Particles (h2) - sc-415625-LAC-2 from Santa Cruz Biotechnology
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KIF24 siRNA (h) - sc-92804 from Santa Cruz Biotechnology
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KIF24 shRNA Plasmid (h) - sc-92804-SH from Santa Cruz Biotechnology
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KIF24 shRNA (h) Lentiviral Particles - sc-92804-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU032431 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11191 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11191 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12838 from Sigma-Aldrich
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KIF24 siRNA (Human) - CRJ7495 from Cohesion Biosciences
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shRNA set against Human KIF24 (NM_194313.2) - SHH325195 from Creative biogene
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Human KIF24 siRNA - orb277996 from Biorbyt
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KIF24 shRNA Plasmid (Human) - CHJ7495 from Cohesion Biosciences
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KIF24 miRNA 3'UTR clone - MiUTR1H-01538 from Creative biogene
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