| Gene Symbol |
SLC1A2
|
| Entrez Gene |
6506
|
| Alt Symbol |
EAAT2, GLT-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 1 (glial high affinity glutamate transporter), member 2
|
| Other Description |
excitatory amino acid transporter 2|excitotoxic amino acid transporter 2|glutamate/aspartate transporter II|sodium-dependent glutamate/aspartate transporter 2
|
| Swissprots |
P43004 U3KQQ4 Q541G6 Q14417 B4DQE9
|
| Accessions |
CAL69850 EAW68141 EAW68142 EAW68143 P43004 AB209444 BAD92681 AF131756 AK054855 AK057674 AK090810 AK122843 BAG53756 AK298769 BAG60911 AL157452 AY066021 AAL57716 BC031313 BC047052 BC132768 AAI32769 BX509751 BX538155 BX648750 CR626999 CR627009 CR627022 CR749842 D85884 BAA28706 DA158200 DA215039 DB465494 S83375 U01824 AAA18900 U03505 AAA50429 Z32517 CAA83532 XM_005253067 XP_005253124 XM_011520284 XP_011518586 XM_011520285 XP_011518587 XM_011520286 XP_011518588 XM_011520287 XP_011518589 NM_001195728 NP_001182657 NM_001252652 NP_001239581 NM_004171 NP_004162
|
| Function |
Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Top Pathways |
Amyotrophic lateral sclerosis (ALS), Glutamatergic synapse
|