SLC1A2

Gene Symbol SLC1A2
Entrez Gene 6506
Alt Symbol EAAT2, GLT-1
Species Human
Gene Type protein-coding
Description solute carrier family 1 (glial high affinity glutamate transporter), member 2
Other Description excitatory amino acid transporter 2|excitotoxic amino acid transporter 2|glutamate/aspartate transporter II|sodium-dependent glutamate/aspartate transporter 2
Swissprots P43004 U3KQQ4 Q541G6 Q14417 B4DQE9
Accessions CAL69850 EAW68141 EAW68142 EAW68143 P43004 AB209444 BAD92681 AF131756 AK054855 AK057674 AK090810 AK122843 BAG53756 AK298769 BAG60911 AL157452 AY066021 AAL57716 BC031313 BC047052 BC132768 AAI32769 BX509751 BX538155 BX648750 CR626999 CR627009 CR627022 CR749842 D85884 BAA28706 DA158200 DA215039 DB465494 S83375 U01824 AAA18900 U03505 AAA50429 Z32517 CAA83532 XM_005253067 XP_005253124 XM_011520284 XP_011518586 XM_011520285 XP_011518587 XM_011520286 XP_011518588 XM_011520287 XP_011518589 NM_001195728 NP_001182657 NM_001252652 NP_001239581 NM_004171 NP_004162
Function Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
Subcellular Location Membrane; Multi-pass membrane protein.
Top Pathways Amyotrophic lateral sclerosis (ALS), Glutamatergic synapse

EAAT2 Antibody - 3838 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from mouse and rat brain using EAAT2 Antibody.

EAAT2 (E-1) - sc-365634 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
EAAT2 (E-1): sc-365634. Western blot analysis of EAAT2 expression in HeLa (A) and HT-1080 (B) whole cell lysates.

EAAT2 (H-85) - sc-15317 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
EAAT2 (H-85): sc-15317. Western blot analysis of EAAT2 expression in mouse brain (A) and rat brain (B) tissue extracts.

EAAT2 (K-16) - sc-31582 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

EAAT2 (S-18) - sc-31581 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

EAAT2 (N-19) - sc-7760 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
EAAT2 (N-19): sc-7760. Western blot analysis of EAAT2 expression in rat brain extract.

EAAT2 (20) - sc-135892 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
EAAT2 (20): sc-135892. Western blot analysis of EAAT2 expression in rat cerebrum tissue extract.

Anti-EAAT2 antibody - ab41621 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-EAAT2 antibody (ab41621) at 1 µg/mlLane 1 : Brain (Mouse) Mouse Tissue LysateLane 2 : Brain (Rat) Tissue LysateLysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.

Anti-EAAT2 antibody - ab77039 from Abcam

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
IHC image of EAAT2 staining in Human normal cerebral cortex formalin fixed paraffin embedded tissue section, performed on a Leica Bond™ system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab77039, 10µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-EAAT2 antibody - ab85882 from Abcam

Host Sheep
Clonality Polyclonal

Anti-EAAT2 antibody - ab126829 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-EAAT2 antibody (ab126829) at 1/500 dilutionLane 1 : EAAT2 positive controlLane 2 : Hippocampal membrane lysate

Anti-EAAT2 antibody - ab172212 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-EAAT2 antibody (ab172212) at 1 µg/mlLane 1 : EAAT2 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Rabbit IgG at 1/7500 dilution

Anti-EAAT2 antibody [1H8] - ab49645 from Abcam

Prices $376.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal
Clone 1H8
Human brain, normal adult cerebellum: IHC-P staining for excitatory amino acid transporter 2 using ab49645. Note membrane staining of glial cells.

Anti-EAAT2 antibody [1H8], prediluted - ab75445 from Abcam

Prices $376.00
Sizes 7 ml
Host Mouse
Clonality Monoclonal
Clone 1H8
Formalin-fixed, paraffin-embedded human brain stained with ab75445 using peroxidase conjugate and AEC chromogen. Note cytoplasmic and processes staining of glial cells.

Anti-EAAT2 antibody [EPR10769(2)] - ab178401 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10769(2)
All lanes : Anti-EAAT2 antibody [EPR10769(2)] (ab178401) at 1/1000 dilutionLane 1 : SH-SY5Y cell lysateLane 2 : HeLa cell lysateLane 3 : Human fetal brain lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilutiondeveloped using the ECL technique

Anti-Glutamate Transporter 1 antibody - ab106289 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Glutamate Transporter 1 antibody (ab106289) at 1/1000 dilutionLane 1 : Protein extract from Rat brainLane 2 : Protein extract from Mouse brain

Anti-SLC1A2 / EAAT2 / GLT-1 Antibody (N-Terminus) - LS-C15457 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC1A2 / EAAT2 / GLT-1 Antibody (C-Terminus) - LS-C15437 from LifeSpan Bioscience

Prices $325.00
Sizes 250 µl
Host Mouse
Clonality Monoclonal

Anti-SLC1A2 / EAAT2 / GLT-1 Antibody (N-Terminus) - LS-C15458 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC1A2 / EAAT2 / GLT-1 Antibody (aa546-565) - LS-C15448 from LifeSpan Bioscience

Prices $530.00
Sizes 50 µl
Host Guinea Pig
Clonality Polyclonal

Anti-SLC1A2 / EAAT2 Antibody (C-Terminus) - LS-C66666 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-SLC1A2 / EAAT2 / GLT-1 Antibody (aa500-550) - LS-C94123 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC1A2 / EAAT2 / GLT-1 Antibody (C-Terminus) - LS-C144601 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC1A2 / EAAT2 / GLT-1 Antibody (clone 1H8) - LS-C87838 from LifeSpan Bioscience

Prices $255.00, $485.00, $645.00
Sizes 100 µl, 500 µl, 1 ml
Host Mouse
Clonality Monoclonal
Clone 1H8
Formalin-fixed, paraffin-embedded human brain stained with peroxidase-conjugate and AEC chromogen. Note cytoplasmic and processes staining of glial cells.

Anti-SLC1A2 / EAAT2 Antibody (aa160-240, Azide-free) - LS-C327452 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
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