| Gene Symbol |
SLC1A7
|
| Entrez Gene |
6512
|
| Alt Symbol |
AAAT, EAAT5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 1 (glutamate transporter), member 7
|
| Other Description |
excitatory amino acid transporter 5|excitatory amino acid transporter 5 (retinal glutamate transporter)|retinal glutamate transporter
|
| Swissprots |
Q9BW45 Q969Z8 Q5VVZ0 O00341
|
| Accessions |
EAX06754 EAX06755 O00341 AB593059 BAJ84006 AB593060 BAJ84007 AB593061 BAJ84008 AK093921 BAG52786 BC000651 AAH00651 BC012119 AAH12119 BC017242 AAH17242 CD672672 DQ892299 ABM83225 DQ895498 ABM86424 JF917096 AEI69348 JX162773 AGA00108 U76362 AAB53971 XM_011542002 XP_011540304 XM_011542003 XP_011540305 NM_001287595 NP_001274524 NM_001287596 NP_001274525 NM_001287597 NP_001274526 NM_006671 NP_006662 NR_109858
|
| Function |
Transports L-glutamate; the L-glutamate uptake is sodium- and voltage-dependent and chloride-independent. Its associated chloride conductance may participate in visual processing.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed primarily in retina. Detectable in liver, heart, muscle and brain.
|
| Top Pathways |
Glutamatergic synapse
|
![Western Blot: SLC1A7 Overexpression Lysate (Adult Normal) [NBP2-04316] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SLC1A7.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2455_SLC1A7%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04316-img0001.jpg)