Gene Symbol | SLC1A7 |
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Entrez Gene | 6512 |
Alt Symbol | AAAT, EAAT5 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 1 (glutamate transporter), member 7 |
Other Description | excitatory amino acid transporter 5|excitatory amino acid transporter 5 (retinal glutamate transporter)|retinal glutamate transporter |
Swissprots | Q9BW45 Q969Z8 Q5VVZ0 O00341 |
Accessions | EAX06754 EAX06755 O00341 AB593059 BAJ84006 AB593060 BAJ84007 AB593061 BAJ84008 AK093921 BAG52786 BC000651 AAH00651 BC012119 AAH12119 BC017242 AAH17242 CD672672 DQ892299 ABM83225 DQ895498 ABM86424 JF917096 AEI69348 JX162773 AGA00108 U76362 AAB53971 XM_011542002 XP_011540304 XM_011542003 XP_011540305 NM_001287595 NP_001274524 NM_001287596 NP_001274525 NM_001287597 NP_001274526 NM_006671 NP_006662 NR_109858 |
Function | Transports L-glutamate; the L-glutamate uptake is sodium- and voltage-dependent and chloride-independent. Its associated chloride conductance may participate in visual processing. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed primarily in retina. Detectable in liver, heart, muscle and brain. |
Top Pathways | Glutamatergic synapse |
EAAT5 CRISPR/Cas9 KO Plasmid (h) - sc-404474 from Santa Cruz Biotechnology
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EAAT5 HDR Plasmid (h) - sc-404474-HDR from Santa Cruz Biotechnology
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EAAT5 Double Nickase Plasmid (h) - sc-404474-NIC from Santa Cruz Biotechnology
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EAAT5 Double Nickase Plasmid (h2) - sc-404474-NIC-2 from Santa Cruz Biotechnology
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EAAT5 CRISPR Activation Plasmid (h) - sc-404474-ACT from Santa Cruz Biotechnology
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EAAT5 CRISPR Activation Plasmid (h2) - sc-404474-ACT-2 from Santa Cruz Biotechnology
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EAAT5 Lentiviral Activation Particles (h) - sc-404474-LAC from Santa Cruz Biotechnology
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EAAT5 Lentiviral Activation Particles (h2) - sc-404474-LAC-2 from Santa Cruz Biotechnology
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EAAT5 siRNA (h) - sc-41944 from Santa Cruz Biotechnology
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EAAT5 shRNA Plasmid (h) - sc-41944-SH from Santa Cruz Biotechnology
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EAAT5 shRNA (h) Lentiviral Particles - sc-41944-V from Santa Cruz Biotechnology
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SLC1A7 RNAi - H00006512-R01 from Novus Biologicals
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MISSION® esiRNA - EHU146391 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19451 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19451 from Sigma-Aldrich
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SLC1A7 siRNA (Human) - CRH4407 from Cohesion Biosciences
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SLC1A7 - MBS8237274 from MyBioSource
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shRNA set against Human SLC1A7 (NM_006671.4) - SHH408968 from Creative biogene
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SLC1A7 shRNA Plasmid (Human) - CHH4407 from Cohesion Biosciences
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SLC1A7 miRNA 3'UTR clone - MiUTR4H-TG08103 from Creative biogene
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