| Gene Symbol |
CLEC12B
|
| Entrez Gene |
387837
|
| Alt Symbol |
UNQ5782
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
C-type lectin domain family 12, member B
|
| Other Description |
C-type lectin domain family 12 member B|macrophage antigen h
|
| Swissprots |
Q6UWF2 Q2HXU8 Q6ZRG0
|
| Accessions |
EAW96135 EAW96136 EAW96137 EAW96138 Q2HXU8 AI655492 AK128243 BAC87350 AK131027 AY358810 AAQ89170 BC036036 BC136805 AAI36806 BC136806 AAI36807 DQ368812 ABC96323 HQ258146 ADR82900 XM_006719070 XP_006719133 XM_006719071 XP_006719134 XM_006719072 XP_006719135 XM_011520658 XP_011518960 XM_011520659 XP_011518961 XM_011520660 XP_011518962 XM_011520661 XP_011518963 XM_011520662 XP_011518964 XM_011520663 XP_011518965 XM_011520664 XP_011518966 XR_242889 XR_931290 NM_001129998 NP_001123470 NM_205852 NP_995324
|
| Function |
Cell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. {ECO:0000269|PubMed:17562706}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:17562706}; Single-pass type II membrane protein {ECO:0000269|PubMed:17562706}.
|
| Tissue Specificity |
Detected in colon, heart, kidney, liver, lung, mammary gland, ovary, spleen and testis. {ECO:0000269|PubMed:17562706}.
|
![Western Blot: CLEC12B Overexpression Lysate (Adult Normal) [NBP2-09494] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CLEC12B.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10305_CLEC12B%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-09494-img0001.jpg)