Gene Symbol | CLEC12B |
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Entrez Gene | 387837 |
Alt Symbol | UNQ5782 |
Species | Human |
Gene Type | protein-coding |
Description | C-type lectin domain family 12, member B |
Other Description | C-type lectin domain family 12 member B|macrophage antigen h |
Swissprots | Q6UWF2 Q2HXU8 Q6ZRG0 |
Accessions | EAW96135 EAW96136 EAW96137 EAW96138 Q2HXU8 AI655492 AK128243 BAC87350 AK131027 AY358810 AAQ89170 BC036036 BC136805 AAI36806 BC136806 AAI36807 DQ368812 ABC96323 HQ258146 ADR82900 XM_006719070 XP_006719133 XM_006719071 XP_006719134 XM_006719072 XP_006719135 XM_011520658 XP_011518960 XM_011520659 XP_011518961 XM_011520660 XP_011518962 XM_011520661 XP_011518963 XM_011520662 XP_011518964 XM_011520663 XP_011518965 XM_011520664 XP_011518966 XR_242889 XR_931290 NM_001129998 NP_001123470 NM_205852 NP_995324 |
Function | Cell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. {ECO:0000269|PubMed:17562706}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:17562706}; Single-pass type II membrane protein {ECO:0000269|PubMed:17562706}. |
Tissue Specificity | Detected in colon, heart, kidney, liver, lung, mammary gland, ovary, spleen and testis. {ECO:0000269|PubMed:17562706}. |
CLEC-12B CRISPR/Cas9 KO Plasmid (h) - sc-409107 from Santa Cruz Biotechnology
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CLEC-12B HDR Plasmid (h) - sc-409107-HDR from Santa Cruz Biotechnology
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CLEC-12B Double Nickase Plasmid (h) - sc-409107-NIC from Santa Cruz Biotechnology
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CLEC-12B Double Nickase Plasmid (h2) - sc-409107-NIC-2 from Santa Cruz Biotechnology
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CLEC-12B CRISPR Activation Plasmid (h) - sc-409107-ACT from Santa Cruz Biotechnology
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CLEC-12B CRISPR Activation Plasmid (h2) - sc-409107-ACT-2 from Santa Cruz Biotechnology
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CLEC-12B Lentiviral Activation Particles (h) - sc-409107-LAC from Santa Cruz Biotechnology
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CLEC-12B Lentiviral Activation Particles (h2) - sc-409107-LAC-2 from Santa Cruz Biotechnology
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CLEC-12B siRNA (h) - sc-96052 from Santa Cruz Biotechnology
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CLEC-12B shRNA Plasmid (h) - sc-96052-SH from Santa Cruz Biotechnology
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CLEC-12B shRNA (h) Lentiviral Particles - sc-96052-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU084461 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6199 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6199 from Sigma-Aldrich
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CLEC12B siRNA (Human) - CRJ7762 from Cohesion Biosciences
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CLEC12B - MBS8223516 from MyBioSource
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shRNA set against Human CLEC12B (NM_205852.2) - SHH264929 from Creative biogene
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CLEC12B shRNA Plasmid (Human) - CHJ7762 from Cohesion Biosciences
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CLEC12B miRNA 3'UTR clone - MiUTR4H-TG10915 from Creative biogene
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