| Gene Symbol |
IRF2BP2
|
| Entrez Gene |
359948
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
interferon regulatory factor 2 binding protein 2
|
| Other Description |
IRF-2-binding protein 2|interferon regulatory factor 2-binding protein 2
|
| Swissprots |
B1AM35 Q8N351 Q7Z5L9 B1AM36 Q8WUH8 Q6P083 Q7Z5L8
|
| Accessions |
EAW69996 Q7Z5L9 AK054864 AK056930 AK300375 BAG62111 AK309579 AY278023 AAP78944 AY278024 AAP78945 BC020516 AAH20516 BC041989 BC053539 BC065759 AAH65759 BC160054 AAI60054 BE408503 CD640986 NM_001077397 NP_001070865 NM_182972 NP_892017
|
| Function |
Acts as a transcriptional corepressor in a IRF2- dependent manner; this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscle. {ECO:0000269|PubMed:12799427, ECO:0000269|PubMed:20702774, ECO:0000269|PubMed:21576369}.
|
| Subcellular Location |
Cytoplasm. Nucleus.
|