| Gene Symbol |
DACT2
|
| Entrez Gene |
168002
|
| Alt Symbol |
C6orf116, DAPPER2, DPR2, bA503C24.7
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dishevelled-binding antagonist of beta-catenin 2
|
| Other Description |
dapper antagonist of catenin 2|dapper homolog 2|dapper homolog 2, antagonist of beta-catenin|dapper, antagonist of beta-catenin, homolog 2
|
| Swissprots |
Q8WYW2 Q2NKJ2 Q569G0 Q5SW24
|
| Accessions |
EAW47467 Q5SW24 AF318336 AAL55843 BC092498 AAH92498 BC111764 AAI11765 BC111790 AAI11791 BX329974 BX377941 CV427932 DR004351 XM_011535507 XP_011533809 XM_011535508 XP_011533810 NM_001286350 NP_001273279 NM_001286351 NP_001273280 NM_214462 NP_999627 NR_104425
|
| Function |
Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling (By similarity). {ECO:0000250}.
|