DACT2

Gene Symbol DACT2
Entrez Gene 168002
Alt Symbol C6orf116, DAPPER2, DPR2, bA503C24.7
Species Human
Gene Type protein-coding
Description dishevelled-binding antagonist of beta-catenin 2
Other Description dapper antagonist of catenin 2|dapper homolog 2|dapper homolog 2, antagonist of beta-catenin|dapper, antagonist of beta-catenin, homolog 2
Swissprots Q8WYW2 Q2NKJ2 Q569G0 Q5SW24
Accessions EAW47467 Q5SW24 AF318336 AAL55843 BC092498 AAH92498 BC111764 AAI11765 BC111790 AAI11791 BX329974 BX377941 CV427932 DR004351 XM_011535507 XP_011533809 XM_011535508 XP_011533810 NM_001286350 NP_001273279 NM_001286351 NP_001273280 NM_214462 NP_999627 NR_104425
Function Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling (By similarity). {ECO:0000250}.

Dapper2 (C-12) - sc-167589 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Dapper2 (N-14) - sc-167591 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Dact2 antibody - ab79042 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Dact2 antibody (ab79042) at 1 µg/ml + SK N SH cell lysate at 15 µg

Anti-Dact2 antibody - ab42099 from Abcam

Prices $242.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of Dact2 staining in human normal kidney formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab42099, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

Anti-DPR2 / DACT2 Antibody (N-Terminus) IHC-plus™ - LS-B3853 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-DACT2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3853 concentration 5 ug/ml.

Dact2 Antibody - NBP1-76955 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Dact2 Antibody [NBP1-76955] - SK-N-SH cell lysate with Dact2 antibody at 1 ug/ml.

Dact2 Antibody - NBP1-52230 from Novus Biologicals

Prices $399.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Dact2 Antibody [NBP1-52230] Staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

Dact2 Antibody - NBP1-88756 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Dact2 Antibody [NBP1-88756] - staining of human placenta shows cytoplasmic positivity in trophoblastic cells.

Dact2 Antibody - NBP1-88755 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: Dact2 Antibody [NBP1-88755] - Staining of human liver shows strong granular cytoplasmic positivity in hepatocytes.

Rabbit Anti-Dact2 Polyclonal Antibody - bs-11836R from Bioss

Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-Dact2 Polyclonal Antibody, Unconjugated (bs-11836R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Rabbit Anti-Dact2 Polyclonal Antibody, Cy3 Conjugated - bs-11836R-Cy3 from Bioss

Host Rabbit
Clonality Polyclonal

Rabbit Anti-Dact2 Polyclonal Antibody, Cy5 Conjugated - bs-11836R-Cy5 from Bioss

Host Rabbit
Clonality Polyclonal

Rabbit Anti-Dact2 Polyclonal Antibody, Cy7 Conjugated - bs-11836R-Cy7 from Bioss

Host Rabbit
Clonality Polyclonal

Rabbit Anti-Dact2 Polyclonal Antibody, HRP Conjugated - bs-11836R-HRP from Bioss

Host Rabbit
Clonality Polyclonal

Anti-DACT2 antibody produced in rabbit - PRS4859 from Sigma-Aldrich

Prices $347.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-Dact2: <B>Cat. No. PRS4859</B> Western blot analysis of Dact2 in SK-N-SH cell lysate with Dact2 antibody at 1 μg/mL.

Anti-DACT2 antibody produced in rabbit - HPA030252 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-DACT2: <B>Cat. No. HPA030252</B>: Immunohistochemical staining of human liver shows strong granular cytoplasmic positivity in hepatocytes.

Anti-DACT2 antibody produced in rabbit - HPA030251 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-DACT2: <B>Cat. No. HPA030251</B>: Immunohistochemical staining of human prostate shows strong granular positivity in glandular cells.

Dact2 antibody - GTX85373 from GeneTex

Prices $299.00
Sizes 100 μg
Anti-Dact2 antibody used in Immunohistochemistry. GTX85373
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